This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.

Drug	Interaction
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Amphetamine	The serum concentration of Amphetamine can be decreased when it is combined with Calcium ascorbate.
Benzphetamine	The serum concentration of Benzphetamine can be decreased when it is combined with Calcium ascorbate.
Bleomycin	The therapeutic efficacy of Bleomycin can be decreased when used in combination with Calcium ascorbate.
Bortezomib	The therapeutic efficacy of Bortezomib can be decreased when used in combination with Calcium ascorbate.
Chlorpropamide	Calcium ascorbate may decrease the excretion rate of Chlorpropamide which could result in a higher serum level.

Food Interactions

No interactions found.

Products

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Product Ingredients

Ingredient	UNII	CAS	InChI Key
Calcium ascorbate dihydrate	183E4W213W	5743-28-2	RGJHWLDSRIHFKY-FWCDDDAWSA-L

Active Moieties

Name	Kind	UNII	CAS	InChI Key
Ascorbic acid	salt	PQ6CK8PD0R	50-81-7	CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Over the Counter Products

Name	Dosage	Strength	Route	Labeller	Marketing Start	Marketing End
Ascorbate C-500	Capsule	500 mg	Oral	Seroyal International Inc.	1998-12-31	2001-08-09
Buffered Vitamin C 1000mg	Tablet	1000 mg	Oral	General Nutrition Canada Inc.	1997-11-26	2005-08-05
Calcium Ascorbate 1000mg	Capsule	1000 mg / cap	Oral	Natural Factors Nutritional Products Ltd.	1996-12-31	2007-08-07
Calcium Ascorbate Crystals 1250mg/0.25tsp	Powder	1.25 g / 1.25 mL	Oral	Swiss Herbal Remedies Ltd.	1987-12-31	2009-08-04
Calcium Ascorbate Crystals Vitamin C 1gm/ml	Powder	1 g / mL	Oral	Vita Health Products Inc	1991-12-31	2004-07-26

Mixture Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End
A/o-26 - Caplet	Calcium ascorbate (250 mg) + Beta carotene (7500 unit) + Calcium (75 mg) + Copper (1 mg) + DL-alpha tocopheryl acetate (100 unit) + Folic acid (.4 mg) + Manganese cation (2.5 mg) + Racemethionine (50 mg) + Selenium (100 mcg) + Zinc (7.5 mg)	Tablet	Oral	Enviro Tech International Canada	1996-12-19	1999-07-26
Aces Caplet	Calcium ascorbate (350 mg) + Beta carotene (15000 unit) + Chromium (25 mcg) + Selenium (100 mcg) + Vitamin E (200 unit) + Zinc (25 mg)	Tablet	Oral	Nu Life Nutrition Ltd.	1997-08-15	2005-03-15
Aces Tab	Calcium ascorbate (350 mg) + Cholecalciferol (200 unit) + Chromium (25 mcg) + Selenium (100 mcg) + Vitamin A (5000 unit) + Vitamin E (200 unit) + Zinc (25 mg)	Tablet	Oral	Nu Life Nutrition Ltd.	1987-12-31	2005-03-15
Acti-megascorb Crystals Pwr	Calcium ascorbate (2 g / 5 mL) + Calcium ascorbate (260 mg / 5 mL)	Powder	Oral	Acti Form Ltd.	1991-12-31	2005-03-21
Acti-megascorb Crystals Pwr	Calcium ascorbate (2 g / 5 mL) + Calcium ascorbate (260 mg / 5 mL)	Powder	Oral	Acti Form Ltd.	1991-12-31	2005-03-21

Unapproved/Other Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End
Cavan One	Calcium ascorbate dihydrate (25 mg/1) + Calcium (150 mg/1) + Cholecalciferol (170 [iU]/1) + DL-alpha tocopheryl acetate (30 [iU]/1) + Doconexent (260 mg/1) + Ferrous asparto glycinate (7 mg/1) + Folic acid (1 mg/1) + Icosapent (40 mg/1) + Iron (20 mg/1) + Linoleic acid (30 mg/1) + Pyridoxine hydrochloride (25 mg/1) + alpha-Linolenic acid (30 mg/1)	Capsule, gelatin coated	Oral	Seton Pharmaceuticals	2009-10-30	2011-11-27
Ferrex 150 Forte Plus	Calcium ascorbate dihydrate (60 mg/1) + Calcium threonate (0.8 mg/1) + Cyanocobalamin (25 ug/1) + Folic acid (1 mg/1) + Iron (150 mg/1) + Succinic acid (50 mg/1)	Capsule	Oral	Breckenridge Pharmaceutical, Inc.	2008-08-01	2012-09-30
Folcaps Care One	Calcium ascorbate dihydrate (24 mg/1) + Biotin (300 mg/1) + Calcium carbonate (100 mg/1) + Calcium threonate (1 mg/1) + Cholecalciferol (800 [iU]/1) + Doconexent (350 mg/1) + Docusate sodium (50 mg/1) + Folic acid (1 mg/1) + Icosapent (100 mg/1) + Iodine (150 ug/1) + Iron (27 mg/1) + Magnesium (50 mg/1) + Nicotinamide (10 mg/1) + Pyridoxine hydrochloride (50 mg/1) + Riboflavin (1.5 mg/1) + Zinc (5 mg/1) + alpha-Linolenic acid (50 mg/1) + alpha-Tocopherol acetate (15 [iU]/1)	Capsule, gelatin coated	Oral	Mayne Pharma	2009-05-01	2016-12-31
Folcaps Omega-3	Calcium ascorbate dihydrate (24 mg/1) + Calcium (150 mg/1) + Calcium threonate (1 mg/1) + Cholecalciferol (170 [iU]/1) + Doconexent (260 mg/1) + Ferrous asparto glycinate (7 mg/1) + Folic acid (1 mg/1) + Icosapent (40 mg/1) + Iron (20 mg/1) + Pyridoxine hydrochloride (25 mg/1) + alpha-Linolenic acid (30 mg/1) + alpha-Tocopherol acetate (30 [iU]/1)	Capsule, gelatin coated	Oral	Mayne Pharma	2011-01-03	2016-12-31
Nestabs ONE	Calcium ascorbate dihydrate (18 mg/1) + Cholecalciferol (6.25 ug/1) + Cyanocobalamin (15 ug/1) + Doconexent (225 mg/1) + Folic acid (1 mg/1) + Iron (38 mg/1) + Magnesium oxide (15 mg/1) + Pyridoxine hydrochloride (30 mg/1) + Tocopherol (10 mg/1) + Zinc oxide (1 mg/1)	Capsule, gelatin coated	Oral	Womens Choice Pharmaceuticals, Llc	2017-07-20	Not applicable

Chemical Identifiers

UNII: J96U0ZD4Y6
CAS number: 5743-27-1
InChI Key: BLORRZQTHNGFTI-ZZMNMWMASA-L
InChI: InChI=1S/2C6H8O6.Ca/c2*7-1-2(8)5-3(9)4(10)6(11)12-5;/h2*2,5,7-10H,1H2;/q;;+2/p-2/t2*2-,5+;/m00./s1
IUPAC Name: calcium bis((2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate)
SMILES: [Ca++].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-]

References

General References

Not Available

External Links

ChemSpider: 22900989
ChEMBL: CHEMBL2146095
Wikipedia: Calcium_ascorbate

Clinical Trials

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Phase	Status	Purpose	Conditions	Count	Start Date	Why Stopped	100+ additional columns
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Pharmacoeconomics

Manufacturers

Not Available

Packagers

Not Available

Dosage Forms

Form	Route	Strength
Tablet	Oral	166.7 mg / tab
Tablet	Oral	1000 mg
Capsule	Oral	1000 mg / cap
Powder	Oral	1.25 g / 1.25 mL
Powder	Oral	1 g / mL
Powder	Oral	4.5 g / 5 mL
Powder	Oral	825 mg / g
Powder	Oral	1.3 g / 1.25 mL
Capsule, gelatin coated	Oral
Tablet	Oral	250 mg / tab
Tablet	Oral	635 mg
Tablet, coated	Oral
Tablet, extended release	Oral
Powder, for solution	Oral
Tablet	Oral	500 mg / tab
Capsule	Oral
Gel	Oral
Capsule	Oral	500 mg / cap
Tablet, effervescent	Oral
Tablet	Oral
Tablet, film coated
Powder
Capsule	Oral	660 mg / cap
Tablet, effervescent	Oral	1000 mg
Capsule	Oral	500 mg
Powder	Oral	1000 mg / 1.25 g
Capsule, liquid filled	Oral
Pill	Oral
Tablet, chewable	Oral
Tablet, film coated	Oral
Kit	Oral
Capsule	Oral	200 mg / cap
Emulsion	Topical
Liquid	Oral
Tablet	Oral	1 g
Tablet	Oral	500 mg
Capsule	Oral	600 mg / cap
Powder	Oral

Prices

Not Available

Patents

Not Available

Properties

State

Not Available

Experimental Properties

Not Available

Predicted Properties

Property	Value	Source
Water Solubility	16.0 mg/mL	ALOGPS
logP	-1.6	ALOGPS
logP	-1.9	Chemaxon
logS	-1.4	ALOGPS
pKa (Strongest Acidic)	4.36	Chemaxon
pKa (Strongest Basic)	-3	Chemaxon
Physiological Charge	-1	Chemaxon
Hydrogen Acceptor Count	5	Chemaxon
Hydrogen Donor Count	3	Chemaxon
Polar Surface Area	110.05 Å²	Chemaxon
Rotatable Bond Count	4	Chemaxon
Refractivity	47.58 m³·mol^-1	Chemaxon
Polarizability	14.48 Å³	Chemaxon
Number of Rings	2	Chemaxon
Bioavailability	1	Chemaxon
Rule of Five	Yes	Chemaxon
Ghose Filter	No	Chemaxon
Veber's Rule	No	Chemaxon
MDDR-like Rule	No	Chemaxon

Predicted ADMET Features

Not Available

Spectra

Mass Spec (NIST): Not Available
Spectra: Not Available
Chromatographic Properties: Collision Cross Sections (CCS)
Not Available

Drug created at July 06, 2018 22:11 / Updated at September 15, 2024 21:55

Calcium ascorbate

Identification

Structure for Calcium ascorbate (DB14483)

Pharmacology

Interactions

Products

Categories

Chemical Identifiers

References

Clinical Trials

Clinical Trial & Rare Diseases Add-on Data Package

Pharmacoeconomics

Properties

Spectra

Collision Cross Sections (CCS)