This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Lithium hydroxide
DrugBank Accession Number
DB14506
Background

Used for tryptophan determinations in proteins & foods.

Type
Small Molecule
Groups
Approved, Withdrawn
Structure
Thumb
Weight
Average: 23.95
Monoisotopic: 24.01874309
Chemical Formula
HLiO
Synonyms
  • Lithium hydrate
  • Lithium hydroxide anhydrous
  • Lithiumhydroxid

Pharmacology

Indication

Not Available

Pharmacology
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Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AceclofenacAceclofenac may decrease the excretion rate of Lithium hydroxide which could result in a higher serum level.
AcemetacinAcemetacin may decrease the excretion rate of Lithium hydroxide which could result in a higher serum level.
AcetazolamideThe absorption of Lithium hydroxide can be decreased when combined with Acetazolamide.
AcetophenazineLithium hydroxide may increase the neurotoxic activities of Acetophenazine.
Acetylsalicylic acidAcetylsalicylic acid may decrease the excretion rate of Lithium hydroxide which could result in a higher serum level.
AlclofenacAlclofenac may decrease the excretion rate of Lithium hydroxide which could result in a higher serum level.
AlimemazineLithium hydroxide may increase the neurotoxic activities of Alimemazine.
AminophenazoneAminophenazone may decrease the excretion rate of Lithium hydroxide which could result in a higher serum level.
AminophyllineThe serum concentration of Lithium hydroxide can be decreased when it is combined with Aminophylline.
AmiodaroneThe risk or severity of adverse effects can be increased when Amiodarone is combined with Lithium hydroxide.
Interactions
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Food Interactions
Not Available

Products

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Product Ingredients
IngredientUNIICASInChI Key
Lithium hydroxide monohydrateG51XLP968G1310-66-3GLXDVVHUTZTUQK-UHFFFAOYSA-M
Active Moieties
NameKindUNIICASInChI Key
Lithium cationionic8H8Z5UER667439-93-2HBBGRARXTFLTSG-UHFFFAOYSA-N
Generic Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Lithium Hydroxide MonohydrateSolution8 meq/5mLOralMorton Grove Pharmaceuticals, Inc.1986-05-212011-04-06US flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
903YL31JAS
CAS number
1310-65-2
InChI Key
WMFOQBRAJBCJND-UHFFFAOYSA-M
InChI
InChI=1S/Li.H2O/h;1H2/q+1;/p-1
IUPAC Name
lithium(1+) hydroxide
SMILES
[Li+].[OH-]

References

General References
Not Available
ChemSpider
3802
RxNav
1546375
ChEBI
33979
Wikipedia
Lithium_hydroxide

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
SolutionOral8 meq/5mL
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP0ChemAxon
pKa (Strongest Acidic)3.09ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m3·mol-1ChemAxon
Polarizability1.78 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created at July 11, 2018 21:53 / Updated at May 07, 2021 21:38