This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Zinc cation
DrugBank Accession Number
DB14532
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Thumb
Weight
Average: 65.409
Monoisotopic: 63.929146578
Chemical Formula
Zn
Synonyms
  • Zinc ion
  • Zinc ion(2+)
  • Zinc, ion (Zn2+)
  • Zinc(2+)
  • Zinc(II)

Pharmacology

Indication

Not Available

Pharmacology
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Associated Conditions
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
CabotegravirThe serum concentration of Cabotegravir can be decreased when it is combined with Zinc cation.
CarbamazepineZinc cation can cause a decrease in the absorption of Carbamazepine resulting in a reduced serum concentration and potentially a decrease in efficacy.
CeftibutenZinc cation can cause a decrease in the absorption of Ceftibuten resulting in a reduced serum concentration and potentially a decrease in efficacy.
CephalexinZinc cation can cause a decrease in the absorption of Cephalexin resulting in a reduced serum concentration and potentially a decrease in efficacy.
CinoxacinZinc cation can cause a decrease in the absorption of Cinoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
CiprofloxacinZinc cation can cause a decrease in the absorption of Ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
DeferasiroxZinc cation can cause a decrease in the absorption of Deferasirox resulting in a reduced serum concentration and potentially a decrease in efficacy.
DeferiproneZinc cation can cause a decrease in the absorption of Deferiprone resulting in a reduced serum concentration and potentially a decrease in efficacy.
DelafloxacinZinc cation can cause a decrease in the absorption of Delafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
DemeclocyclineZinc cation can cause a decrease in the absorption of Demeclocycline resulting in a reduced serum concentration and potentially a decrease in efficacy.
Interactions
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Food Interactions
Not Available

Products

Products2
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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Orajel 3X Medicated For Toothache and GumZinc cation (1.5 mg/1g) + Benzocaine (200 mg/1g) + Levomenthol (2.6 mg/1g)GelTopicalChurch & Dwight Co., Inc.2019-11-01Not applicableUS flag
Orajel 4X Medicated For Toothache and GumZinc cation (1.5 mg/1g) + Benzalkonium chloride (1.3 mg/1g) + Benzocaine (200 mg/1g) + Levomenthol (5 mg/1g)GelTopicalChurch & Dwight Co., Inc.2019-11-01Not applicableUS flag
Orajel 4X Medicated For Toothache and Gum, CreamZinc cation (1.5 mg/1g) + Benzalkonium chloride (1.3 mg/1g) + Benzocaine (200 mg/1g) + Levomenthol (2.6 mg/1g)CreamTopicalChurch & Dwight Co., Inc.2019-11-01Not applicableUS flag
Orajel 4X Medicated For Toothache and Gum, CreamZinc cation (1.5 mg/1g) + Benzalkonium chloride (1.3 mg/1g) + Benzocaine (200 mg/1g) + Menthol (2.6 mg/1g)CreamTopicalChurch & Dwight Co., Inc.2019-11-01Not applicableUS flag
Orajel 4X Medicated PM For Toothache and GumZinc cation (1.5 mg/1g) + Benzalkonium chloride (1.3 mg/1g) + Benzocaine (200 mg/1g) + Levomenthol (2.6 mg/1g)CreamTopicalChurch & Dwight Co., Inc.2019-11-01Not applicableUS flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
13S1S8SF37
CAS number
23713-49-7
InChI Key
PTFCDOFLOPIGGS-UHFFFAOYSA-N
InChI
InChI=1S/Zn/q+2
IUPAC Name
zinc(2+) ion
SMILES
[Zn++]

References

General References
Not Available
ChemSpider
29723
BindingDB
16
RxNav
1546264
ChEBI
29105
ChEMBL
CHEMBL1236970
PDBe Ligand
ZN
PDB Entries
12ca / 1a0b / 1a0q / 1a1f / 1a1g / 1a1h / 1a1i / 1a1j / 1a1k / 1a1l
show 18477 more

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
GelTopical
CreamTopical
Tablet, delayed releaseOral10 mg
CapsuleOral15 mg
Tablet25 mg
Tablet, film coatedOral25 mg
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP0.16ChemAxon
pKa (Strongest Acidic)3.09ChemAxon
Physiological Charge2ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m3·mol-1ChemAxon
Polarizability1.78 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-03di-9000000000-0cd08967c771fb645329
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-03di-9000000000-0cd08967c771fb645329
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-03di-9000000000-0cd08967c771fb645329
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-03di-9000000000-29976d3ebd17b2d11a4b
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-03di-9000000000-29976d3ebd17b2d11a4b
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-03di-9000000000-29976d3ebd17b2d11a4b

Drug created at July 12, 2018 19:44 / Updated at May 29, 2021 18:15