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Identification
- Summary
Gallium chloride Ga-67 is a radioactive isotope of gallium usually complexed with sodium citrate used to test for Hodgkin's disease, lymphoma, and bronchogenic carcinoma, and acute inflammatory lesions.
- Generic Name
- Gallium chloride Ga-67
- DrugBank Accession Number
- DB14550
- Background
Gallium chloride Ga-67 is the chloride salt of a gallium radioisotope which is typically complexed with sodium citrate to generate gallium citrate Ga 67, which can be used to image certain cancers and inflammatory lesions.1
- Type
- Small Molecule
- Groups
- Approved
- Structure
Structure for Gallium chloride Ga-67 (DB14550)
- Weight
- Average: 173.28
Monoisotopic: 171.834763 - Chemical Formula
- Cl3Ga
- Synonyms
- Gallium (67Ga) chloride
- Gallium (Ga-67) chloride
- Gallium chloride Ga 67
- Gallium chloride, Ga-67
- Gallium chloride,Ga-67
Pharmacology
- Indication
Following complexation with sodium citrate to yield gallium citrate Ga 67, gallium chloride Ga-67 is used to demonstrate the presence of Hodgkin's disease, lymphomas, bronchogenic carcinomas, and some acute inflammatory lesions.1
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Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Diagnostic agent Carcinoma, bronchogenic •••••••••••• Diagnostic agent Hodgkins disease (hd) •••••••••••• Diagnostic agent Malignant lymphomas •••••••••••• Diagnostic agent Acute inflammatory lesions •••••••••••• - Contraindications & Blackbox Warnings
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Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
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Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- No interactions found.
Products
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Name Kind UNII CAS InChI Key Gallium cation Ga-67 ionic 99T03J52W0 Not Available CKHJYUSOUQDYEN-OIOBTWANSA-N - Brand Name Prescription Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Gallium Citrate Ga-67 Injection, solution 2 mCi/1mL Intravenous Curium US LLC 2008-02-21 Not applicable US 
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- A04B19O2B0
- CAS number
- Not Available
- InChI Key
- UPWPDUACHOATKO-MPZFSRPWSA-K
- InChI
- InChI=1S/3ClH.Ga/h3*1H;/q;;;+3/p-3/i;;;1-3
- IUPAC Name
- (67Ga)gallium(3+) trichloride
- SMILES
- [Cl-].[Cl-].[Cl-].[67Ga+3]
References
- General References
- FDA Approved Drug Products: Gallium Citrate Ga 67 Intravenous Injection [Link]
- External Links
Clinical Trials
- Clinical Trials
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Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Injection, solution Intravenous 2 mCi/1mL - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 11.2 mg/mL ALOGPS logP 1.95 ALOGPS logP 0 Chemaxon logS -1.2 ALOGPS pKa (Strongest Acidic) 2.68 Chemaxon Physiological Charge 3 Chemaxon Hydrogen Acceptor Count 0 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 0 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 0 m3·mol-1 Chemaxon Polarizability 1.78 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at July 12, 2018 21:55 / Updated at October 06, 2020 17:43