Gallium chloride Ga-67
Identification
- Summary
Gallium chloride Ga-67 is a radioactive isotope of gallium usually complexed with sodium citrate used to test for Hodgkin's disease, lymphoma, and bronchogenic carcinoma, and acute inflammatory lesions.
- Generic Name
- Gallium chloride Ga-67
- DrugBank Accession Number
- DB14550
- Background
Gallium chloride Ga-67 is the chloride salt of a gallium radioisotope which is typically complexed with sodium citrate to generate gallium citrate Ga 67, which can be used to image certain cancers and inflammatory lesions.1
- Type
- Small Molecule
- Groups
- Approved
- Structure
- Weight
- Average: 173.28
Monoisotopic: 171.834763 - Chemical Formula
- Cl3Ga
- Synonyms
- Gallium (67Ga) chloride
- Gallium (Ga-67) chloride
- Gallium chloride Ga 67
- Gallium chloride, Ga-67
- Gallium chloride,Ga-67
Pharmacology
- Indication
Following complexation with sodium citrate to yield gallium citrate Ga 67, gallium chloride Ga-67 is used to demonstrate the presence of Hodgkin's disease, lymphomas, bronchogenic carcinomas, and some acute inflammatory lesions.1
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
- Contraindications & Blackbox Warnings
- Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API
- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- No interactions found.
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Active Moieties
Name Kind UNII CAS InChI Key Gallium cation Ga-67 ionic 99T03J52W0 Not Available CKHJYUSOUQDYEN-OIOBTWANSA-N - Brand Name Prescription Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Gallium Citrate Ga-67 Injection, solution 2 mCi/1mL Intravenous Curium US LLC 2008-02-21 Not applicable US
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- A04B19O2B0
- CAS number
- Not Available
- InChI Key
- UPWPDUACHOATKO-MPZFSRPWSA-K
- InChI
- InChI=1S/3ClH.Ga/h3*1H;/q;;;+3/p-3/i;;;1-3
- IUPAC Name
- (67Ga)gallium(3+) trichloride
- SMILES
- [Cl-].[Cl-].[Cl-].[67Ga+3]
References
- General References
- FDA Approved Drug Products: Gallium Citrate Ga 67 Intravenous Injection [Link]
- External Links
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Injection, solution Intravenous 2 mCi/1mL - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 11.2 mg/mL ALOGPS logP 1.95 ALOGPS logP 0 Chemaxon logS -1.2 ALOGPS pKa (Strongest Acidic) 2.68 Chemaxon Physiological Charge 3 Chemaxon Hydrogen Acceptor Count 0 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 0 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 0 m3·mol-1 Chemaxon Polarizability 1.78 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Drug created at July 12, 2018 21:55 / Updated at October 06, 2020 17:43