This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Phosphorus P-32
DrugBank Accession Number
DB14551
Background

Phosphorus P-32 is a radioactive isotope of phosphorus with beta particle-emitting radiocytotoxic activity. Emitted by phosphorus P32, beta particles directly damage cellular DNA and, by ionizing intracellular water to produce several types of cytotoxic free radicals and superoxides, indirectly damage intracellular biological macromolecules, resulting in tumor cell death.

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 34.998
Monoisotopic: 34.99738226
Chemical Formula
H3P
Synonyms
  • P-32
  • Phosphorus-32
  • Phosphorus, P-32

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Brand Name Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
P32 Sodium PhosphateSolution10 mCi/4mLIntravenousAnazao Health Corporation2012-06-19Not applicableUS flag
P32 Sodium PhosphateInjection, suspension5 mCi/1mLInterstitial; Intra-articular; Intraperitoneal; IntrapleuralAnazao Health Corporation2012-06-19Not applicableUS flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
P32 Sodium PhosphatePhosphorus P-32 (10 mCi/4mL)SolutionIntravenousAnazao Health Corporation2012-06-19Not applicableUS flag
P32 Sodium PhosphatePhosphorus P-32 (5 mCi/1mL)Injection, suspensionInterstitial; Intra-articular; Intraperitoneal; IntrapleuralAnazao Health Corporation2012-06-19Not applicableUS flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
690284A407
CAS number
14596-37-3
InChI Key
XYFCBTPGUUZFHI-OUBTZVSYSA-N
InChI
InChI=1S/H3P/h1H3/i1+1
IUPAC Name
(32P)phosphane
SMILES
[H][32P]([H])[H]

References

General References
Not Available
KEGG Compound
C19162
ChemSpider
24925
RxNav
258478

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Injection, suspensionInterstitial; Intra-articular; Intraperitoneal; Intrapleural5 mCi/1mL
SolutionIntravenous10 mCi/4mL
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP-0.68ChemAxon
pKa (Strongest Basic)-5.5ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity7.6 m3·mol-1ChemAxon
Polarizability2.7 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created at July 12, 2018 21:57 / Updated at June 12, 2020 17:42