Phosphorus P-32
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Phosphorus P-32
- DrugBank Accession Number
- DB14551
- Background
Phosphorus P-32 is a radioactive isotope of phosphorus with beta particle-emitting radiocytotoxic activity. Emitted by phosphorus P32, beta particles directly damage cellular DNA and, by ionizing intracellular water to produce several types of cytotoxic free radicals and superoxides, indirectly damage intracellular biological macromolecules, resulting in tumor cell death.
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 34.998
Monoisotopic: 34.99738226 - Chemical Formula
- H3P
- Synonyms
- P-32
- Phosphorus-32
- Phosphorus, P-32
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Contraindications & Blackbox Warnings
- Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.
- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Brand Name Prescription Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image P32 Sodium Phosphate Solution 10 mCi/4mL Intravenous Anazao Health Corporation 2012-06-19 Not applicable US P32 Sodium Phosphate Injection, suspension 5 mCi/1mL Interstitial; Intra-articular; Intraperitoneal; Intrapleural Anazao Health Corporation 2012-06-19 Not applicable US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image P32 Sodium Phosphate Phosphorus P-32 (10 mCi/4mL) Solution Intravenous Anazao Health Corporation 2012-06-19 Not applicable US P32 Sodium Phosphate Phosphorus P-32 (5 mCi/1mL) Injection, suspension Interstitial; Intra-articular; Intraperitoneal; Intrapleural Anazao Health Corporation 2012-06-19 Not applicable US
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 690284A407
- CAS number
- 14596-37-3
- InChI Key
- XYFCBTPGUUZFHI-OUBTZVSYSA-N
- InChI
- InChI=1S/H3P/h1H3/i1+1
- IUPAC Name
- (32P)phosphane
- SMILES
- [H][32P]([H])[H]
References
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Injection, suspension Interstitial; Intra-articular; Intraperitoneal; Intrapleural 5 mCi/1mL Solution Intravenous 10 mCi/4mL - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source logP -0.68 Chemaxon pKa (Strongest Basic) -5.5 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 0 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 0 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 7.6 m3·mol-1 Chemaxon Polarizability 2.7 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Drug created at July 12, 2018 21:57 / Updated at June 12, 2020 17:42