Ethylhexylglycerin

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name

Ethylhexylglycerin

DrugBank Accession Number

DB14557

Background

An emollient solvent with antimicrobial activity.

Type

Small Molecule

Groups

Experimental

Structure

Similar Structures

Weight: Average: 204.31
Monoisotopic: 204.172544633
Chemical Formula: C₁₁H₂₄O₃

Synonyms

3-(2-Ethylhexyloxy)propane-1,2-diol
Octoxyglycerin

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Pharmacology

Indication: Not Available
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Pharmacodynamics: Not Available
Mechanism of action: Not Available
Absorption: Not Available
Volume of distribution: Not Available
Protein binding: Not Available
Metabolism: Not Available
Route of elimination: Not Available
Half-life: Not Available
Clearance: Not Available
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Toxicity: Not Available
Pathways: Not Available
Pharmacogenomic Effects/ADRs: Not Available

Interactions

Drug Interactions: This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions: Not Available

Products

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Over the Counter Products

Name	Dosage	Strength	Route	Labeller	Marketing Start	Marketing End	Region	Image
Cluederm Aqua Solution Cleansys	Liquid	5 mg/500mL	Topical	Classys Inc.	2018-07-19	2019-03-29
Lady Goong	Liquid	1 g/100g	Vaginal	Lady House Co., Ltd.	2020-10-17	Not applicable

Mixture Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End
AnubisMed	Ethylhexylglycerin (0.025 g/50mL) + Ammonia (2.75 g/50mL) + Ascorbyl glucoside (0.25 g/50mL) + Ethanol (6.3 mL/50mL) + Glycolic acid (17 g/50mL) + Hexylresorcinol (1 g/50mL) + Hydroxyethyl cellulose (0.34875 g/50mL) + Isopropyl alcohol (0.75 g/50mL) + Kojic acid (2.5 g/50mL) + Lactic acid (5 g/50mL) + Phenoxyethanol (0.225 g/50mL) + Propylene glycol (0.5 g/50mL) + Salicylic acid (1 g/50mL) + Water (7.333 mL/50mL)	Liquid	Topical	ANUBIS COSMETICS SL	2022-11-04	2027-07-01
Disinfectant Cleaning Wipes	Ethylhexylglycerin (0.12 g/1601) + Benzalkonium chloride (0.12 g/1601) + Glycerin (0.12 g/1601) + Phenoxyethanol (0.6 g/1601) + Propylene glycol (0.12 g/1601)	Cloth	Extracorporeal	Reynard (Ningbo) Biotechnology Co., Ltd.	2020-04-17	2020-05-29
Disinfectant Cleaning Wipes	Ethylhexylglycerin (0.12 g/1601) + Benzalkonium chloride (0.12 g/1601) + Glycerin (0.12 g/1601) + Phenoxyethanol (0.6 g/1601) + Propylene glycol (0.12 g/1601)	Cloth	Extracorporeal	Reynard (Ningbo) Biotechnology Co., Ltd.	2020-04-17	2020-05-29
Disinfectant Cleaning Wipes	Ethylhexylglycerin (0.12 g/1601) + Benzalkonium chloride (0.12 g/1601) + Didecyldimethylammonium chloride (0.24 g/1601) + Glycerin (0.12 g/1601) + Phenoxyethanol (0.6 g/1601) + Propylene glycol (0.12 g/1601)	Cloth	Extracorporeal	Reynard (Ningbo) Biotechnology Co., Ltd.	2020-06-12	Not applicable
Disinfecting Wipes	Ethylhexylglycerin (0.12 g/1601) + Benzalkonium chloride (0.12 g/1601) + Didecyldimethylammonium chloride (0.24 g/1601) + Glycerin (0.12 g/1601) + Phenoxyethanol (0.6 g/1601) + Propylene glycol (0.12 g/1601)	Cloth	Extracorporeal	Reynard (Ningbo) Biotechnology Co., Ltd.	2020-04-17	Not applicable

Unapproved/Other Products

Name	Ingredients	Dosage	Route	Labeller	Marketing Start	Marketing End
Cluederm Aqua Solution Cleansys	Ethylhexylglycerin (5 mg/500mL)	Liquid	Topical	Classys Inc.	2018-07-19	2019-03-29
Disinfectant Cleaning Wipes	Ethylhexylglycerin (0.12 g/1601) + Benzalkonium chloride (0.12 g/1601) + Glycerin (0.12 g/1601) + Phenoxyethanol (0.6 g/1601) + Propylene glycol (0.12 g/1601)	Cloth	Extracorporeal	Reynard (Ningbo) Biotechnology Co., Ltd.	2020-04-17	2020-05-29
Disinfectant Cleaning Wipes	Ethylhexylglycerin (0.12 g/1601) + Benzalkonium chloride (0.12 g/1601) + Glycerin (0.12 g/1601) + Phenoxyethanol (0.6 g/1601) + Propylene glycol (0.12 g/1601)	Cloth	Extracorporeal	Reynard (Ningbo) Biotechnology Co., Ltd.	2020-04-17	2020-05-29
Disinfectant Cleaning Wipes	Ethylhexylglycerin (0.12 g/1601) + Benzalkonium chloride (0.12 g/1601) + Didecyldimethylammonium chloride (0.24 g/1601) + Glycerin (0.12 g/1601) + Phenoxyethanol (0.6 g/1601) + Propylene glycol (0.12 g/1601)	Cloth	Extracorporeal	Reynard (Ningbo) Biotechnology Co., Ltd.	2020-06-12	Not applicable
Disinfecting Wipes	Ethylhexylglycerin (0.12 g/1601) + Benzalkonium chloride (0.12 g/1601) + Didecyldimethylammonium chloride (0.24 g/1601) + Glycerin (0.12 g/1601) + Phenoxyethanol (0.6 g/1601) + Propylene glycol (0.12 g/1601)	Cloth	Extracorporeal	Reynard (Ningbo) Biotechnology Co., Ltd.	2020-04-17	Not applicable

Chemical Identifiers

UNII: 147D247K3P
CAS number: 70445-33-9
InChI Key: NCZPCONIKBICGS-UHFFFAOYSA-N
InChI: InChI=1S/C11H24O3/c1-3-5-6-10(4-2)8-14-9-11(13)7-12/h10-13H,3-9H2,1-2H3
IUPAC Name: 3-[(2-ethylhexyl)oxy]propane-1,2-diol
SMILES: CCCCC(CC)COCC(O)CO

References

General References

Not Available

External Links

ChemSpider: 8034793
RxNav: 1367134
Wikipedia: Ethylhexylglycerin

Clinical Trials

Clinical Trials

Phase	Status	Purpose	Conditions	Count

Pharmacoeconomics

Manufacturers

Not Available

Packagers

Not Available

Dosage Forms

Form	Route	Strength
Liquid	Topical
Liquid	Topical	5 mg/500mL
Cloth	Extracorporeal
Swab	Topical
Liquid	Cutaneous
Liquid	Vaginal	1 g/100g

Prices

Not Available

Patents

Not Available

Properties

State

Not Available

Experimental Properties

Not Available

Predicted Properties

Property	Value	Source
Water Solubility	2.73 mg/mL	ALOGPS
logP	2.14	ALOGPS
logP	1.83	Chemaxon
logS	-1.9	ALOGPS
pKa (Strongest Acidic)	13.64	Chemaxon
pKa (Strongest Basic)	-3	Chemaxon
Physiological Charge	0	Chemaxon
Hydrogen Acceptor Count	3	Chemaxon
Hydrogen Donor Count	2	Chemaxon
Polar Surface Area	49.69 Å²	Chemaxon
Rotatable Bond Count	9	Chemaxon
Refractivity	57.42 m³·mol^-1	Chemaxon
Polarizability	25.1 Å³	Chemaxon
Number of Rings	0	Chemaxon
Bioavailability	1	Chemaxon
Rule of Five	Yes	Chemaxon
Ghose Filter	Yes	Chemaxon
Veber's Rule	No	Chemaxon
MDDR-like Rule	No	Chemaxon

Predicted ADMET Features

Not Available

Spectra

Mass Spec (NIST)

Not Available

Spectra

Spectrum	Spectrum Type	Splash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)	Predicted LC-MS/MS	splash10-01p9-9300000000-c6e6e94b20f1857b73f2
Predicted MS/MS Spectrum - 10V, Negative (Annotated)	Predicted LC-MS/MS	splash10-01q9-9710000000-304f32d47409432726e4
Predicted MS/MS Spectrum - 20V, Positive (Annotated)	Predicted LC-MS/MS	splash10-05as-9000000000-2b2627bb3f37907f898e
Predicted MS/MS Spectrum - 20V, Negative (Annotated)	Predicted LC-MS/MS	splash10-08i0-5900000000-17933fbef8f1da4ad6de
Predicted MS/MS Spectrum - 40V, Positive (Annotated)	Predicted LC-MS/MS	splash10-0a6u-9000000000-2db9dc2c1d6b4a04db62
Predicted MS/MS Spectrum - 40V, Negative (Annotated)	Predicted LC-MS/MS	splash10-0f6t-9600000000-d2c38e32b21b216c0d2a
Predicted 1H NMR Spectrum	1D NMR	Not Applicable
Predicted 13C NMR Spectrum	1D NMR	Not Applicable

Chromatographic Properties

Collision Cross Sections (CCS)

Adduct	CCS Value (Å²)	Source type	Source
[M-H]-	143.652	predicted	DeepCCS 1.0 (2019)
[M+H]+	147.55989	predicted	DeepCCS 1.0 (2019)
[M+Na]+	156.9225	predicted	DeepCCS 1.0 (2019)

Drug created at July 20, 2018 16:05 / Updated at June 12, 2020 16:53

Ethylhexylglycerin

Identification

Structure for Ethylhexylglycerin (DB14557)

Pharmacology

Interactions

Products

Categories

Chemical Identifiers

References

Clinical Trials

Pharmacoeconomics

Properties

Spectra

Collision Cross Sections (CCS)