Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Influenza B virus B/Maryland/15/2016 antigen (propiolactone inactivated)
- DrugBank Accession Number
- DB14593
- Background
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen". This defence includes the production of humoral immunity through the development of antibodies (through memory B cells) and of cell-mediated immunity through the production of T-lymphocytes. Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy the virus as there are circulating antibodies that recognize that particular component of the virus that it was previously exposed to.
There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated influenza vaccine (LAIV). Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised individuals. In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques. Live vaccines maintain their replicative ability.
- Type
- Biotech
- Groups
- Approved
- Biologic Classification
- Vaccines
Inactivated - Synonyms
- Not Available
Pharmacology
- Indication
Not Available
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Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Afluria Influenza B virus B/Maryland/15/2016 antigen (propiolactone inactivated) (15 ug/0.5mL) + Influenza A virus A/Singapore/GP1908/2015 IVR-180A (H1N1) antigen (propiolactone inactivated) (15 ug/0.5mL) + Influenza A virus A/Singapore/INFIMH-16-0019/2016 IVR-186 (H3N2) antigen (propiolactone inactivated) (15 ug/0.5mL) Injection, suspension Intramuscular Seqirus S.R.L. 2011-07-15 2019-06-30 US 
Afluria Influenza B virus B/Maryland/15/2016 antigen (propiolactone inactivated) (15 ug/0.5mL) + Influenza A virus A/Singapore/GP1908/2015 IVR-180A (H1N1) antigen (propiolactone inactivated) (15 ug/0.5mL) + Influenza A virus A/Singapore/INFIMH-16-0019/2016 IVR-186 (H3N2) antigen (propiolactone inactivated) (15 ug/0.5mL) Injection, suspension Intramuscular Seqirus S.R.L. 2011-07-15 2019-06-30 US Afluria Quadrivalent Influenza B virus B/Maryland/15/2016 antigen (propiolactone inactivated) (15 ug/0.5mL) + Influenza A virus A/Singapore/GP1908/2015 IVR-180A (H1N1) antigen (propiolactone inactivated) (15 ug/0.5mL) + Influenza A virus A/Singapore/INFIMH-16-0019/2016 IVR-186 (H3N2) antigen (propiolactone inactivated) (15 ug/0.5mL) + Influenza B virus B/Phuket/3073/2013 BVR-1B antigen (propiolactone inactivated) (15 ug/0.5mL) Injection, suspension Intramuscular Seqirus S.R.L. 2016-09-28 2019-06-30 US Afluria Quadrivalent Influenza B virus B/Maryland/15/2016 antigen (propiolactone inactivated) (15 ug/0.5mL) + Influenza A virus A/Brisbane/02/2018 IVR-190 (H1N1) antigen (propiolactone inactivated) (15 ug/0.5mL) + Influenza A virus A/Kansas/14/2017 X-327 (H3N2) antigen (propiolactone inactivated) (15 ug/0.5mL) + Influenza B virus B/Phuket/3073/2013 BVR-1B antigen (propiolactone inactivated) (15 ug/0.5mL) Injection, suspension Intramuscular Seqirus S.R.L. 2016-09-28 2020-06-30 US Afluria Quadrivalent Influenza B virus B/Maryland/15/2016 antigen (propiolactone inactivated) (7.5 ug/0.25mL) + Influenza A virus A/Brisbane/02/2018 IVR-190 (H1N1) antigen (propiolactone inactivated) (7.5 ug/0.25mL) + Influenza A virus A/Kansas/14/2017 X-327 (H3N2) antigen (propiolactone inactivated) (7.5 ug/0.25mL) + Influenza B virus B/Phuket/3073/2013 BVR-1B antigen (propiolactone inactivated) (7.5 ug/0.25mL) Injection, suspension Intramuscular Seqirus S.R.L. 2019-07-02 2020-06-30 US
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- MS1B94SD2A
- CAS number
- Not Available
References
- General References
- Not Available
- External Links
- Not Available
Clinical Trials
- Clinical Trials
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Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Injection, suspension Intramuscular - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
Drug created at August 19, 2018 21:16 / Updated at June 12, 2020 16:53