Edetate disodium

DB14600ApprovedInvestigationalVet approvedSmall molecule

Edetate disodium is a polyvalent ion chelator indicated for emergency treatment of hypercalcemia and digitalis toxicity associated ventricular arrhythmias. A medication used to treat high levels of calcium or digoxin.

Chemical structure of Edetate disodium
Mechanism
Curator reviewed · 2 references
Primary indication
Edetate disodium is indicated for emergency treatment of hypercalcemia and digitalis toxicity associated ventricular arrhythmias.Curator reviewed · 2 structured indications
Formula / weight
C10H14N2Na2O8 · 336.2063 g/mol (avg)
First approval
Canada, 1972 · United States, 2006
Brand names
  • Endrate

Resolves to

Compound
UNII8NLQ36F6MMCAS139-33-3ChEMBLCHEMBL1749ChEBI64734PubChem8759KEGGD03945
Clinical / RWD
RxNorm1299924
Structure
InChIKeyZGTMUACCHSMWAC-UHFFFAOYSA-LSMILES[Na+].[Na+].OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O

What you can answer from here — as of September 23, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
1Drug interactionStructured to mechanism, not free text
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4Clinical trialsPhase, status and sponsor resolved per trial
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2Structured indicationsCondition, population, route and combination as fields, not prose
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2ContraindicationsEach with its own population and attribute set
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11Marketed productsAcross 4 countries and 9 labellers
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16+ReferencesStructured and connected to the statements they support
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