Perphenazine enanthate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Perphenazine enanthate
DrugBank Accession Number
DB14651
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 516.14
Monoisotopic: 515.2373263
Chemical Formula
C28H38ClN3O2S
Synonyms
  • Perphenazine enantate

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
1,2-BenzodiazepineThe risk or severity of CNS depression can be increased when 1,2-Benzodiazepine is combined with Perphenazine enanthate.
AcebutololThe serum concentration of Acebutolol can be increased when it is combined with Perphenazine enanthate.
AcetazolamideThe risk or severity of CNS depression can be increased when Acetazolamide is combined with Perphenazine enanthate.
AcetohexamideThe therapeutic efficacy of Acetohexamide can be decreased when used in combination with Perphenazine enanthate.
AcetophenazineThe risk or severity of CNS depression can be increased when Acetophenazine is combined with Perphenazine enanthate.
Food Interactions
Not Available

Categories

Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as phenothiazines. These are polycyclic aromatic compounds containing a phenothiazine moiety, which is a linear tricyclic system that consists of a two benzene rings joined by a para-thiazine ring.
Kingdom
Organic compounds
Super Class
Organoheterocyclic compounds
Class
Benzothiazines
Sub Class
Phenothiazines
Direct Parent
Phenothiazines
Alternative Parents
Alkyldiarylamines / Diarylthioethers / Fatty acid esters / N-alkylpiperazines / 1,4-thiazines / Benzenoids / Aryl chlorides / Trialkylamines / Carboxylic acid esters / Amino acids and derivatives
show 7 more
Substituents
1,4-diazinane / Alkyldiarylamine / Amine / Amino acid or derivatives / Aromatic heteropolycyclic compound / Aryl chloride / Aryl halide / Aryl thioether / Azacycle / Benzenoid
show 24 more
Molecular Framework
Aromatic heteropolycyclic compounds
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
Z6RS3DKN8J
CAS number
17528-28-8
InChI Key
PWEGQJCIAMJJHC-UHFFFAOYSA-N
InChI
InChI=1S/C28H38ClN3O2S/c1-2-3-4-5-11-28(33)34-21-20-31-18-16-30(17-19-31)14-8-15-32-24-9-6-7-10-26(24)35-27-13-12-23(29)22-25(27)32/h6-7,9-10,12-13,22H,2-5,8,11,14-21H2,1H3
IUPAC Name
2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethyl heptanoate
SMILES
CCCCCCC(=O)OCCN1CCN(CCCN2C3=CC=CC=C3SC3=C2C=C(Cl)C=C3)CC1

References

General References
Not Available
PubChem Compound
23623915
ChemSpider
56601
ZINC
ZINC000030691684
Wikipedia
Perphenazine

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.000557 mg/mLALOGPS
logP6.41ALOGPS
logP6.61Chemaxon
logS-6ALOGPS
pKa (Strongest Basic)7.48Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count4Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area36.02 Å2Chemaxon
Rotatable Bond Count13Chemaxon
Refractivity148.28 m3·mol-1Chemaxon
Polarizability59.95 Å3Chemaxon
Number of Rings4Chemaxon
Bioavailability0Chemaxon
Rule of FiveNoChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleYesChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-014i-0000090000-386f624af15ba30e524a
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-03di-0001090000-fc6e15e043125fa2868a
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-03di-1903000000-302615fe4964b0dfde26
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-0gbi-0737940000-f2f3c5eca74ea278558f
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-0pc1-9400000000-ba46d32fe5f96160f4dd
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-01p9-2449510000-b24593558587076519e1
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-223.58284
predicted
DeepCCS 1.0 (2019)
[M+H]+226.04222
predicted
DeepCCS 1.0 (2019)
[M+Na]+233.40285
predicted
DeepCCS 1.0 (2019)

Drug created at September 01, 2018 23:43 / Updated at June 12, 2020 16:53