Combretastatin A4

DB14680ExperimentalSmall molecule

Combretastatin A4: Overview.

Chemical structure of Combretastatin A4
Mechanism
Curator reviewed
Formula / weight
C18H20O5 · 316.353 g/mol (avg)
Also known as
2'-deoxycombretastatin A1 · CA4 · Combrestatin A4 · Combretastatin 4 · Combretastatin A-4
Code names
NSC-613729 · NSC-817373

Resolves to

Compound
UNII16U6OP69RQCAS117048-59-6ChEMBLCHEMBL67ChEBI181391
Structure
InChIKeyHVXBOLULGPECHP-WAYWQWQTSA-NSMILESCOC1=CC=C(\C=C/C2=CC(OC)=C(OC)C(OC)=C2)C=C1O
Targets
P07437TUBB

What you can answer from here — as of July 07, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
39Drug interactionsStructured to mechanism, not free text
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11+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Combretastatin A4, and which of those have an active Phase 3 trial?

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