Chloramine-T
This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Summary
Chloramine-T is a chlorinated disinfectant of the genitals and injured skin.
- Generic Name
- Tosylchloramide
Commonly known or available as Chloramine-T - DrugBank Accession Number
- DB14708
- Background
Tosylchloramide, also known as chloramine-T, is a chlorinated and deprotonated sulfonamide used as a mild disinfectant. It is not stable in the water dissolved form.
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Tosylchloramide (DB14708)
- Weight
- Average: 205.66
Monoisotopic: 204.9964274 - Chemical Formula
- C7H8ClNO2S
- Synonyms
- N-chloro-p-toluenesulfonamide
- N-chlorotoluene-p-sulfonamide
Pharmacology
- Indication
Not Available
Accelerate your drug discovery research with the industry’s only fully connected ADMET dataset, ideal for:Accelerate your drug discovery research with our fully connected ADMET dataset- Associated Conditions
- Contraindications & Blackbox Warnings
Contraindications & Blackbox WarningsWith our commercial data, access important information on dangerous risks, contraindications, and adverse effects.Our Blackbox Warnings cover Risks, Contraindications, and Adverse Effects- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Reduce medical errorsand improve treatment outcomes with our comprehensive & structured data on drug adverse effects.Reduce medical errors & improve treatment outcomes with our adverse effects data- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareBenzylpenicillin Tosylchloramide may decrease the excretion rate of Benzylpenicillin which could result in a higher serum level. Magnesium The serum concentration of Magnesium can be decreased when it is combined with Tosylchloramide. 
Improve patient outcomesBuild effective decision support tools with the industry’s most comprehensive drug-drug interaction checker.Learn more - Food Interactions
- Not Available
Products
Comprehensive & structured drug product infoFrom application numbers to product codes, connect different identifiers through our commercial datasets.Easily connect various identifiers back to our datasets- Product Ingredients
Ingredient UNII CAS InChI Key Chloramine-T 328AS34YM6 127-65-1 VDQQXEISLMTGAB-UHFFFAOYSA-N Chloramine-T trihydrate 4IU6VSV0EI 7080-50-4 NZYOAGBNMCVQIV-UHFFFAOYSA-N - International/Other Brands
- Chloramin T / Chloraseptin / Chlorazol / Clorina / Disifin / Halamid / Minachlor / Trichlorol
Categories
- ATC Codes
- D08AX04 — Tosylchloramide sodium
- Drug Categories
- Amines
- Anti-Infective Agents
- Anti-Infective Agents, Local
- Antiseptics and Disinfectants
- Benzene Derivatives
- Chlorine Compounds
- Compounds used in a research, industrial, or household setting
- Dermatologicals
- Disinfectants
- Indicators and Reagents
- Laboratory Chemicals
- Noxae
- Oxidants
- Sulfonamides
- Sulfones
- Sulfur Compounds
- Toxic Actions
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- UF17KA8AC5
- CAS number
- 144-86-5
- InChI Key
- NXTVQNIVUKXOIL-UHFFFAOYSA-N
- InChI
- InChI=1S/C7H8ClNO2S/c1-6-2-4-7(5-3-6)12(10,11)9-8/h2-5,9H,1H3
- IUPAC Name
- N-chloro-4-methylbenzene-1-sulfonamide
- SMILES
- CC1=CC=C(C=C1)S(=O)(=O)NCl
References
- General References
- AIFA Product Information: STERIDROLO (chloramine) powder [Link]
- External Links
- ChemSpider
- 29119
- ChEBI
- 53782
- ChEMBL
- CHEMBL1625750
- ZINC
- ZINC000008576333
- Wikipedia
- Chloramine-T
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Powder, for solution Topical - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.388 mg/mL ALOGPS logP -1.6 ALOGPS logP 1.85 ChemAxon logS -2.7 ALOGPS pKa (Strongest Acidic) 4.89 ChemAxon Physiological Charge -1 ChemAxon Hydrogen Acceptor Count 2 ChemAxon Hydrogen Donor Count 1 ChemAxon Polar Surface Area 46.17 Å2 ChemAxon Rotatable Bond Count 1 ChemAxon Refractivity 48.59 m3·mol-1 ChemAxon Polarizability 19.31 Å3 ChemAxon Number of Rings 1 ChemAxon Bioavailability 1 ChemAxon Rule of Five Yes ChemAxon Ghose Filter Yes ChemAxon Veber's Rule No ChemAxon MDDR-like Rule No ChemAxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Drug created on September 30, 2018 19:47 / Updated on July 29, 2021 04:17