This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Summary
Chloramine-T is a chlorinated disinfectant of the genitals and injured skin.
- Generic Name
- Tosylchloramide
Commonly known or available as Chloramine-T - DrugBank Accession Number
- DB14708
- Background
Tosylchloramide, also known as chloramine-T, is a chlorinated and deprotonated sulfonamide used as a mild disinfectant. It is not stable in the water dissolved form.
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Tosylchloramide (DB14708)
- Weight
- Average: 205.66
Monoisotopic: 204.9964274 - Chemical Formula
- C7H8ClNO2S
- Synonyms
- N-chloro-p-toluenesulfonamide
- N-chlorotoluene-p-sulfonamide
Pharmacology
- Indication
Not Available
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- Contraindications & Blackbox Warnings
Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareBenzylpenicillin Tosylchloramide may decrease the excretion rate of Benzylpenicillin which could result in a higher serum level. Insulin aspart The risk or severity of hypoglycemia can be increased when Tosylchloramide is combined with Insulin aspart. Insulin beef The risk or severity of hypoglycemia can be increased when Tosylchloramide is combined with Insulin beef. Insulin degludec The risk or severity of hypoglycemia can be increased when Tosylchloramide is combined with Insulin degludec. Insulin detemir The risk or severity of hypoglycemia can be increased when Tosylchloramide is combined with Insulin detemir. Insulin glargine The risk or severity of hypoglycemia can be increased when Tosylchloramide is combined with Insulin glargine. Insulin glulisine The risk or severity of hypoglycemia can be increased when Tosylchloramide is combined with Insulin glulisine. Insulin human The risk or severity of hypoglycemia can be increased when Tosylchloramide is combined with Insulin human. Insulin lispro The risk or severity of hypoglycemia can be increased when Tosylchloramide is combined with Insulin lispro. Insulin pork The risk or severity of hypoglycemia can be increased when Tosylchloramide is combined with Insulin pork. 
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- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Product Ingredients
Ingredient UNII CAS InChI Key Chloramine-T 328AS34YM6 127-65-1 VDQQXEISLMTGAB-UHFFFAOYSA-N Chloramine-T trihydrate 4IU6VSV0EI 7080-50-4 NZYOAGBNMCVQIV-UHFFFAOYSA-N - International/Other Brands
- Chloramin T / Chloraseptin / Chlorazol / Clorina / Disifin / Halamid / Minachlor / Trichlorol
Categories
- ATC Codes
- D08AX04 — Tosylchloramide sodium
- Drug Categories
- Amines
- Anti-Infective Agents
- Anti-Infective Agents, Local
- Antiseptics and Disinfectants
- Benzene Derivatives
- Chlorine Compounds
- Compounds used in a research, industrial, or household setting
- Dermatologicals
- Disinfectants
- Indicators and Reagents
- Laboratory Chemicals
- Noxae
- Oxidants
- Sulfonamides
- Sulfones
- Sulfur Compounds
- Toxic Actions
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- UF17KA8AC5
- CAS number
- 144-86-5
- InChI Key
- NXTVQNIVUKXOIL-UHFFFAOYSA-N
- InChI
- InChI=1S/C7H8ClNO2S/c1-6-2-4-7(5-3-6)12(10,11)9-8/h2-5,9H,1H3
- IUPAC Name
- N-chloro-4-methylbenzene-1-sulfonamide
- SMILES
- CC1=CC=C(C=C1)S(=O)(=O)NCl
References
- General References
- AIFA Product Information: STERIDROLO (chloramine) powder [Link]
- External Links
- ChemSpider
- 29119
- ChEBI
- 53782
- ChEMBL
- CHEMBL1625750
- ZINC
- ZINC000008576333
- Wikipedia
- Chloramine-T
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Powder, for solution Topical 2.5 g Powder, for solution Topical 5 g - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.388 mg/mL ALOGPS logP -1.6 ALOGPS logP 1.85 ChemAxon logS -2.7 ALOGPS pKa (Strongest Acidic) 4.89 ChemAxon Physiological Charge -1 ChemAxon Hydrogen Acceptor Count 2 ChemAxon Hydrogen Donor Count 1 ChemAxon Polar Surface Area 46.17 Å2 ChemAxon Rotatable Bond Count 1 ChemAxon Refractivity 48.59 m3·mol-1 ChemAxon Polarizability 19.31 Å3 ChemAxon Number of Rings 1 ChemAxon Bioavailability 1 ChemAxon Rule of Five Yes ChemAxon Ghose Filter Yes ChemAxon Veber's Rule No ChemAxon MDDR-like Rule No ChemAxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Drug created at September 30, 2018 19:47 / Updated at August 09, 2022 08:59