Tenivastatin
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Tenivastatin
- DrugBank Accession Number
- DB14714
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 436.5815
Monoisotopic: 436.282489012 - Chemical Formula
- C25H40O6
- Synonyms
- Tenivastatin
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Product Ingredients
Ingredient UNII CAS InChI Key Tenivastatin sodium 2L6JSY5YGL 101314-97-0 RLWRROYWKHUVKF-OKDJMAGBSA-M
Categories
- Drug Categories
- Not Available
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as medium-chain hydroxy acids and derivatives. These are hydroxy acids with a 6 to 12 carbon atoms long side chain.
- Kingdom
- Organic compounds
- Super Class
- Organic acids and derivatives
- Class
- Hydroxy acids and derivatives
- Sub Class
- Medium-chain hydroxy acids and derivatives
- Direct Parent
- Medium-chain hydroxy acids and derivatives
- Alternative Parents
- Fatty alcohols / Medium-chain fatty acids / Hydroxy fatty acids / Fatty acid esters / Branched fatty acids / Beta hydroxy acids and derivatives / Dicarboxylic acids and derivatives / Secondary alcohols / Carboxylic acid esters / Carboxylic acids show 3 more
- Substituents
- Alcohol / Aliphatic homopolycyclic compound / Beta-hydroxy acid / Branched fatty acid / Carbonyl group / Carboxylic acid / Carboxylic acid derivative / Carboxylic acid ester / Dicarboxylic acid or derivatives / Fatty acid ester show 10 more
- Molecular Framework
- Aliphatic homopolycyclic compounds
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 9L6M5TH46B
- CAS number
- 121009-77-6
- InChI Key
- XWLXKKNPFMNSFA-HGQWONQESA-N
- InChI
- InChI=1S/C25H40O6/c1-6-25(4,5)24(30)31-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-18(26)13-19(27)14-22(28)29/h7-8,11,15-16,18-21,23,26-27H,6,9-10,12-14H2,1-5H3,(H,28,29)/t15-,16-,18+,19+,20-,21-,23-/m0/s1
- IUPAC Name
- (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid
- SMILES
- [H][C@@](O)(CC[C@@]1([H])[C@@H](C)C=CC2=C[C@H](C)C[C@H](OC(=O)C(C)(C)CC)[C@]12[H])C[C@@H](O)CC(O)=O
References
- General References
- Not Available
- External Links
- Human Metabolome Database
- HMDB0061047
- ChemSpider
- 58263
- BindingDB
- 18375
- ChEMBL
- CHEMBL1201391
- ZINC
- ZINC000003833877
- PDBe Ligand
- SIM
- PDB Entries
- 1hw9 / 4xw2 / 6kjf
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.0402 mg/mL ALOGPS logP 4.22 ALOGPS logP 3.79 Chemaxon logS -4 ALOGPS pKa (Strongest Acidic) 4.21 Chemaxon pKa (Strongest Basic) -2.7 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 104.06 Å2 Chemaxon Rotatable Bond Count 11 Chemaxon Refractivity 121.18 m3·mol-1 Chemaxon Polarizability 49.23 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 219.6866811 predictedDarkChem Lite v0.1.0 [M-H]- 209.3535 predictedDeepCCS 1.0 (2019) [M-H]- 219.6866811 predictedDarkChem Lite v0.1.0 [M-H]- 209.3535 predictedDeepCCS 1.0 (2019) [M+H]+ 217.7052811 predictedDarkChem Lite v0.1.0 [M+H]+ 211.17839 predictedDeepCCS 1.0 (2019) [M+H]+ 217.7052811 predictedDarkChem Lite v0.1.0 [M+H]+ 211.17839 predictedDeepCCS 1.0 (2019) [M+Na]+ 219.7911811 predictedDarkChem Lite v0.1.0 [M+Na]+ 216.80818 predictedDeepCCS 1.0 (2019) [M+Na]+ 219.7911811 predictedDarkChem Lite v0.1.0 [M+Na]+ 216.80818 predictedDeepCCS 1.0 (2019)
Drug created at October 11, 2018 22:25 / Updated at February 21, 2021 18:54