ONO-2952

DB14802InvestigationalSmall molecule

ONO-2952 is under investigation in clinical trial NCT01887002 (Study to Evaluate the Effects of ONO-2952 on Pain Perception Produced by Rectal Distention in Female Subjects With Diarrhea-Predominant Irritable Bowel Syndrome...

Mechanism: Pharmacologically active on Translocator protein
Curator reviewed
Formula / weight: C₂₂H₂₀ClFN₂O₂ · 398.86 g/mol (avg)
Code names: ONO-2952

Resolves to

Compound

UNIIZH8CPX4YNBCAS895169-20-7

Structure

InChIKeyZBQMTQGDBFZUBG-NRFANRHFSA-NSMILESCOC1=C(C=CC(Cl)=C1)[C@@H]1N(CC2(CC2)C2=C1NC1=C2C(F)=CC=C1)C(C)=O

Targets

P30536TSPO

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

4Clinical trialsPhase, status and sponsor resolved per trial

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with ONO-2952, and which of those have an active Phase 3 trial?

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