PF-5190457

DB14870InvestigationalSmall molecule

PF-5190457 is under investigation in clinical trial NCT01522807 (A Study Of Three PF-05190457 Formulations In Healthy Volunteers).

Mechanism: Pharmacologically active on Growth hormone secretagogue receptor type 1
Curator reviewed
Formula / weight: C₂₉H₃₂N₆OS · 512.68 g/mol (avg)
Code names: PF-05190457 · PF-5190457

Resolves to

Compound

Structure

InChIKeyZIUDADZJCKGWKR-AREMUKBSSA-NSMILESCC1=CN2C=C(CC(=O)N3CCC4(CN(C4)[C@@H]4CCC5=C4C=CC(=C5)C4=CC(C)=NC=N4)CC3)N=C2S1

Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

4Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with PF-5190457, and which of those have an active Phase 3 trial?

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