Florbenazine F-18

DB14945InvestigationalSmall molecule

Florbenazine F-18 is under investigation in clinical trial NCT01515384 (A Trial of 18F-AV-133 Positron Emission Tomography (PET)).

Mechanism: Pharmacologically active on Synaptic vesicular amine transporter
Curator reviewed
Formula / weight: C₂₁H₃₂FNO₃ · 364.492 g/mol (avg)
Also known as: 18F-AV-133 · Florbenazine f 18

Resolves to

Compound

Structure

InChIKeyGNKGXQHHUUEYQV-WTHAECTESA-NSMILESCOC1=C(OCCC[18F])C=C2CCN3C[C@@H](CC(C)C)[C@H](O)C[C@@H]3C2=C1

Targets

What you can answer from here — as of July 07, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

5Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Florbenazine F-18, and which of those have an active Phase 3 trial?

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