This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Ribose
- DrugBank Accession Number
- DB15073
- Background
Ribose is under investigation in clinical trial NCT01727479 (Ribose and Sport Performance).
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 150.1299
Monoisotopic: 150.05282343 - Chemical Formula
- C5H10O5
- Synonyms
- aldehydo-D-ribose
- D-ribo-2,3,4,5-tetrahydroxyvaleraldehyde
- D-Ribose
- Ribose
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Contraindications & Blackbox Warnings
- Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.
- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 681HV46001
- CAS number
- 50-69-1
- InChI Key
- PYMYPHUHKUWMLA-LMVFSUKVSA-N
- InChI
- InChI=1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5-/m0/s1
- IUPAC Name
- (2R,3R,4R)-2,3,4,5-tetrahydroxypentanal
- SMILES
- [H]C(=O)[C@H](O)[C@H](O)[C@H](O)CO
References
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 2 Completed Treatment 5'-Nucleotidase Syndrome 1 2 Completed Treatment Fibromyalgia 1 2 Completed Treatment Heart Failure, Diastolic 1 2 Withdrawn Treatment Congestive Heart Failure (CHF) 1 1 Recruiting Treatment Advanced Solid Tumors 1 1 Recruiting Treatment EGF-R Positive Non-Small Cell Lung Cancer / Non-small Cell Lung Carcinoma (Adenocarcinoma) 1 1 Unknown Status Treatment Breast Neoplasm Malignant Female / Radiotherapy Side Effects / Triple-Negative Breast Neoplasm 1 1, 2 Not Yet Recruiting Treatment Carcinosarcoma of the Fallopian Tubes / Ovarian Cancer / Ovarian Carcinoma / Platinum-resistant Ovarian Cancer / Primary Peritoneal Cancer 1 1, 2 Terminated Treatment Solid Tumors 1 0 Active Not Recruiting Treatment Prostate Cancer 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 380.0 mg/mL ALOGPS logP -2.3 ALOGPS logP -2.9 Chemaxon logS 0.4 ALOGPS pKa (Strongest Acidic) 12.34 Chemaxon pKa (Strongest Basic) -3 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 4 Chemaxon Polar Surface Area 97.99 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 31.38 m3·mol-1 Chemaxon Polarizability 13.39 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key GC-MS Spectrum - GC-MS (1 MEOX; 4 TMS) GC-MS splash10-0udi-1920000000-2a376699e06455c76ff7 GC-MS Spectrum - GC-MS (1 MEOX; 4 TMS) GC-MS splash10-0uxr-0941000000-7b9d79f55ddb22a39810 Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS Not Available
Drug created at May 20, 2019 14:47 / Updated at June 12, 2020 16:53