NAV

Fludeoxyglucose

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Fludeoxyglucose is a radiopharmaceutical indicated for PET scans.

Generic Name
Fludeoxyglucose
DrugBank Accession Number
DB15107
Background

Fludeoxyglucose is under investigation in clinical trial NCT03262389 (Comparison of F-18 FDG and C-11 Acetate PET in Multiple Myeloma).

Type
Small Molecule
Groups
Investigational
Structure
3D
Similar Structures
Weight
Average: 182.147
Monoisotopic: 182.059051617
Chemical Formula
C6H11FO5
Synonyms
Not Available
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

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Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
ZO2JV75L55
CAS number
29702-43-0
InChI Key
AOYNUTHNTBLRMT-SLPGGIOYSA-N
InChI
InChI=1S/C6H11FO5/c7-3(1-8)5(11)6(12)4(10)2-9/h1,3-6,9-12H,2H2/t3-,4+,5+,6+/m0/s1
IUPAC Name
(2R,3S,4R,5R)-2-fluoro-3,4,5,6-tetrahydroxyhexanal
SMILES
OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](F)C=O

References

General References
  1. AIFA: Efdege (Fluodeoxyglucose) Injection [Link]
ChemSpider
148702
ChEBI
49135
ChEMBL
CHEMBL1908940
ZINC
ZINC000001846431
Wikipedia
Fluorodeoxyglucose_(18F)

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4CompletedDiagnosticPositron-Emission Tomography and Cone-Beam Computed Tomography1
4RecruitingDiagnosticDeep Vein Thrombosis / Lung Disorder / Pulmonary Embolism / Respiratory Diseases / Screening / Undefined / Venous Thromboembolism Diseases1
4TerminatedBasic ScienceAbdominal Aortic Aneurysm (AAA)1
2CompletedDiagnosticCancer1
2CompletedDiagnosticMultiple Myeloma (MM)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Injection, solutionParenteral1 GBq
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility139.0 mg/mLALOGPS
logP-1.8ALOGPS
logP-2.7Chemaxon
logS-0.12ALOGPS
pKa (Strongest Acidic)12.25Chemaxon
pKa (Strongest Basic)-3Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count5Chemaxon
Hydrogen Donor Count4Chemaxon
Polar Surface Area97.99 Å2Chemaxon
Rotatable Bond Count5Chemaxon
Refractivity35.65 m3·mol-1Chemaxon
Polarizability15.52 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-00ke-4900000000-4cddcdd49492d9027c21
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-0a4i-9000000000-ba86c875a092d5c8a5a8
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-0avi-9000000000-97a70bb577ce5cdd1f31
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-03dl-9100000000-a93285cc5c6ddf3a10df
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-052f-9000000000-7b16fed320d58c285cef
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-0005-9000000000-c46b9f8769e60147d76d
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at May 20, 2019 14:50 / Updated at May 14, 2021 01:07