Dorzagliatin

DB15123InvestigationalSmall molecule

Dorzagliatin is under investigation in clinical trial NCT03173391 (Long-term Efficacy and Safety of HMS5552 in T2DM).

Chemical structure of Dorzagliatin
Mechanism
Curator reviewed
Formula / weight
C22H27ClN4O5 · 462.93 g/mol (avg)
Code names
HMS5552

Resolves to

Compound
UNIIX59W6980E8CAS1191995-00-2
Clinical / RWD
ATCA10BX18
Structure
InChIKeyHMUMWSORCUWQJO-QAPCUYQASA-NSMILESCC(C)C[C@H](N1CC(OC2=C(Cl)C=CC=C2)=CC1=O)C(=O)NC1=NN(C[C@@H](O)CO)C=C1
Targets
P35557GCK

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
14Clinical trialsPhase, status and sponsor resolved per trial
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1ATC codeIncluding every combination product, plus 3 drug categories
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3+ReferencesStructured and connected to the statements they support
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