JNJ-42165279

DB15173InvestigationalSmall molecule

Jnj-42165279 is under investigation in clinical trial NCT02498392 (An Efficacy, Safety and Tolerability Study of JNJ-42165279 in Participants With Major Depressive Disorder With Anxious Distress).

Mechanism: Pharmacologically active on Fatty-acid amide hydrolase 1
Curator reviewed
Formula / weight: C₁₈H₁₇ClF₂N₄O₃ · 410.81 g/mol (avg)
Code names: JNJ-42165279

Resolves to

Compound

UNIIAH2E5UQ11YCAS1346528-50-4

Structure

InChIKeyYWGYNGCRVZLMCS-UHFFFAOYSA-NSMILESFC1(F)OC2=CC=C(CN3CCN(CC3)C(=O)NC3=C(Cl)C=CN=C3)C=C2O1

Targets

O00519FAAH

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

7Clinical trialsPhase, status and sponsor resolved per trial

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with JNJ-42165279, and which of those have an active Phase 3 trial?

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