Mibenratide

DB15195InvestigationalSmall molecule

Mibenratide is under investigation in clinical trial NCT01798745 (A Study to Assess the Pharmacokinetics and Pharmacodynamics of JNJ-54452840 in Participants With Heart Failure and Anti-beta1-adrenergic Receptor Autoantibodies).

Chemical structure of Mibenratide
Formula / weight
C87H129N27O30S2 · 2097.27 g/mol (avg)
Also known as
JNJ-54452840

Resolves to

Structure
InChIKeyCQXYENUJCPYPTI-YXJUDSKISA-NSMILESCC(C)[C@@H]1NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H]2CSSC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N2

What you can answer from here — as of April 23, 2025

3Clinical trialsPhase, status and sponsor resolved per trial
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Which companies are running trials of Mibenratide, in which indications and phases, and which of those programs are still active?

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