Fluoroacetic acid F-18
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Fluoroacetic acid F-18
- DrugBank Accession Number
- DB15202
- Background
Fluoroacetic acid F-18 is under investigation in clinical trial NCT01320787 (18-F-Fluoroacetate as PET Imaging Agent).
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 77.045
Monoisotopic: 77.014242004 - Chemical Formula
- C2H3FO2
- Synonyms
- 18F-FLUOROACETATE
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 74Q3U8O789
- CAS number
- 7574-44-9
- InChI Key
- QEWYKACRFQMRMB-KTXUZGJCSA-N
- InChI
- InChI=1S/C2H3FO2/c3-1-2(4)5/h1H2,(H,4,5)/i3-1
- IUPAC Name
- 2-(¹⁸F)fluoroacetic acid
- SMILES
- OC(=O)C[18F]
References
- General References
- Not Available
- External Links
- ChemSpider
- 396929
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 1 Withdrawn Diagnostic Brain Cancer / Breast Cancer / Prostate Cancer 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 87.8 mg/mL ALOGPS logP -0.31 ALOGPS logP -0.15 Chemaxon logS 0.05 ALOGPS pKa (Strongest Acidic) 3.13 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 37.3 Å2 Chemaxon Rotatable Bond Count 1 Chemaxon Refractivity 12.65 m3·mol-1 Chemaxon Polarizability 5.42 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS splash10-004i-9000000000-1a3a617ed1a01dda04e7 Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS splash10-004i-9000000000-56f7331aa68cfae2d546 Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS splash10-03di-9000000000-0af3436a480cb25a1ea2 Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS splash10-01q9-9000000000-52176e5c13f523ac7408 Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS splash10-004i-9000000000-a9210515e02553774ed0 Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS splash10-056r-9000000000-4d7c73fcd6dbde985137 Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at May 20, 2019 14:59 / Updated at June 12, 2020 16:53