Iopofosine I-131

DB15244InvestigationalSmall molecule

Iopofosine I-131 (NM-404 I-131) is under investigation in clinical trial NCT01495663 (Dose Escalation Study of I-131-CLR1404 in Subjects With Cancer That Does Not Respond to Treatment or Has Returned).

Formula / weight: C₂₉H₅₃INO₄P · 641.626 g/mol (avg)
Also known as: 18-(P-(131I )-IODOPHENYL)OCTADECYL PHOSPHOCHOLINE · 18-(p-(131I)-iodophenyl)octadecyl phosphocholine · 2-((HYDROXY((18-(4-(131I)IODOPHENYL)OCTADECYL)OXY)PHOSPHINYL)OXY)-N,N,NTRIMETHYLETHANAMINIUM INNER SALT · iopofosine I 131
Code names: 131I-CLR1404 · 131I-NM-404 · CLR 131 · I-131-CLR1404 · NM-404 I-131

Resolves to

Compound

UNIIR048696O9LCAS873438-88-1ChEMBLCHEMBL4297495

Structure

InChIKeyZOAIEFWMQLYMTF-YRKXUXMHSA-NSMILESC[N+](C)(C)CCOP([O-])(=O)OCCCCCCCCCCCCCCCCCCC1=CC=C([131I])C=C1

What you can answer from here — as of May 26, 2026

10Clinical trialsPhase, status and sponsor resolved per trial

Which companies are running trials of Iopofosine I-131, in which indications and phases, and which of those programs are still active?

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