Ridinilazole
Star0
This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Ridinilazole
- DrugBank Accession Number
- DB15308
- Background
Ridinilazole is under investigation in clinical trial NCT02092935 (A Study of SMT19969 Compared With Vancomycin for the Treatment of Clostridium Difficile-Associated Diarrhoea (CDAD)).
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 388.434
Monoisotopic: 388.143644539 - Chemical Formula
- C24H16N6
- Synonyms
- Ridinilazole
- External IDs
- SMT19969
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 06DX01190R
- CAS number
- 308362-25-6
- InChI Key
- UHQFBTAJFNVZIV-UHFFFAOYSA-N
- InChI
- InChI=1S/C24H16N6/c1-3-19-21(29-23(27-19)15-5-9-25-10-6-15)13-17(1)18-2-4-20-22(14-18)30-24(28-20)16-7-11-26-12-8-16/h1-14H,(H,27,29)(H,28,30)
- IUPAC Name
- 2-(pyridin-4-yl)-6-[2-(pyridin-4-yl)-1H-1,3-benzodiazol-6-yl]-1H-1,3-benzodiazole
- SMILES
- N1C2=CC(=CC=C2N=C1C1=CC=NC=C1)C1=CC2=C(C=C1)N=C(N2)C1=CC=NC=C1
References
- General References
- Not Available
- External Links
- ChemSpider
- 17592423
- BindingDB
- 50134759
- ChEMBL
- CHEMBL3753858
- ZINC
- ZINC000113778168
- PDBe Ligand
- IK7
- Wikipedia
- Ridinilazole
- PDB Entries
- 7z9p
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 3 Completed Treatment Clostridioides Difficile Infection 2 3 Terminated Treatment Clostridioides Difficile Infection 1 2 Completed Treatment Clostridium Difficile Infection (CDI) 2
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.0065 mg/mL ALOGPS logP 4.11 ALOGPS logP 3.81 Chemaxon logS -4.8 ALOGPS pKa (Strongest Acidic) 10.97 Chemaxon pKa (Strongest Basic) 5.41 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 83.14 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 134.9 m3·mol-1 Chemaxon Polarizability 44.18 Å3 Chemaxon Number of Rings 6 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS splash10-000i-0009000000-c2e4c079f9f1ba5378f8 Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS splash10-000i-0009000000-22226df3389e395c75bb Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS splash10-000i-0009000000-285abfecddbc066eba78 Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS splash10-000i-0009000000-2be73e1d2970d0a373c6 Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS splash10-0a4i-0009000000-acdc873dcd04ff6a9251 Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS splash10-06rj-1159000000-06ec795d19b4b1ce4299 Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at May 20, 2019 15:11 / Updated at February 21, 2021 18:55