Xanthohumol

DB15359InvestigationalSmall molecule

Xanthohumol is under investigation in clinical trial NCT01367431 (Xanthohumol and Metabolic Syndrome).

Mechanism: Pharmacologically active on Bile acid receptor, Diacylglycerol O-acyltransferase 2, and Diacylglycerol O-acyltransferase 1
Curator reviewed
Formula / weight: C₂₁H₂₂O₅ · 354.3964 g/mol (avg)

Resolves to

Compound

Structure

InChIKeyORXQGKIUCDPEAJ-YRNVUSSQSA-NSMILESCOC1=C(C(=O)\C=C\C2=CC=C(O)C=C2)C(O)=C(CC=C(C)C)C(O)=C1

Targets

What you can answer from here — as of July 08, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

4Clinical trialsPhase, status and sponsor resolved per trial

11+ReferencesStructured and connected to the statements they support

Which drugs share a target with Xanthohumol, and which of those have an active Phase 3 trial?

Create a free account or log in to explore the full data card.