This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
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Identification
- Summary
Ethyl salicylate is a salicylate indicated in the treatment of sports related pain.
- Generic Name
- Ethyl salicylate
- DrugBank Accession Number
- DB15576
- Background
Not Available
- Type
- Small Molecule
- Groups
- Approved, Experimental
- Structure
Structure for Ethyl salicylate (DB15576)
- Weight
- Average: 166.1739
Monoisotopic: 166.062994186 - Chemical Formula
- C9H10O3
- Synonyms
- Ethyl 2-hydroxybenzoate
- Ethyl o-hydroxybenzoate
- Ethyl salicylate
- Salicyclic acid, ethyl ester
- Salicylic ether
- Salicylic ethyl ester
- External IDs
- FEMA No. 2458
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Used in combination for symptomatic treatment of Arthritis Combination Product in combination with: Glycol salicylate (DB11323), Methyl nicotinate (DB13882), Methyl salicylate (DB09543) ••• ••• •••••••• ••••• Used in combination for symptomatic treatment of Back pain lower back Combination Product in combination with: Glycol salicylate (DB11323), Methyl salicylate (DB09543), Methyl nicotinate (DB13882) ••• ••• •••••••• ••••• Used in combination for symptomatic treatment of Fibromyalgia syndrome Combination Product in combination with: Methyl nicotinate (DB13882), Methyl salicylate (DB09543), Glycol salicylate (DB11323) ••• ••• •••••••• ••••• Used in combination for symptomatic treatment of Rheumatism Combination Product in combination with: Methyl nicotinate (DB13882), Glycol salicylate (DB11323), Methyl salicylate (DB09543) ••• ••• •••••••• ••••• Used in combination for symptomatic treatment of Soreness, muscle Combination Product in combination with: Methyl nicotinate (DB13882), Methyl salicylate (DB09543), Glycol salicylate (DB11323) ••• ••• •••••••• ••••• - Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Deep Heat Sports Pain Relief Spray Ethyl salicylate (5 % w/w) + Glycol salicylate (5 % w/w) + Methyl nicotinate (1.6 % w/w) + Methyl salicylate (1 % w/w) Aerosol, spray Topical ROHTO-MENTHOLATUM (M) SDN. BHD. 2020-09-08 2022-02-08 Malaysia 
Sun Pacer Sunless Tanning Lotion SPF 15 Ethyl salicylate (5 %) + Octinoxate (7 %) + Oxybenzone (4 %) Lotion Topical Amway Corporation 1991-12-31 1999-08-04 Canada 
Ultraplast Analgesic Spray Ethyl salicylate (4.8 %) + Glycol salicylate (4.8 %) + Methyl nicotinate (1.6 %) + Methyl salicylate (.96 %) Aerosol Topical Wallace, Cameron and Company Ltd. 1985-12-31 2000-07-31 Canada
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 555U6TZ2MV
- CAS number
- 118-61-6
- InChI Key
- GYCKQBWUSACYIF-UHFFFAOYSA-N
- InChI
- InChI=1S/C9H10O3/c1-2-12-9(11)7-5-3-4-6-8(7)10/h3-6,10H,2H2,1H3
- IUPAC Name
- ethyl 2-hydroxybenzoate
- SMILES
- CCOC(=O)C1=CC=CC=C1O
References
- General References
- NPRA: Deep Heat Sports Pain Relief (Ethyl Salicylate, Glycol Salicylate, Methyl Nicotinate, and Methyl Salicylate) Topical Aerosol [Link]
- External Links
- Human Metabolome Database
- HMDB0029817
- ChemSpider
- 21105897
- 1546423
- ChEBI
- 88839
- ChEMBL
- CHEMBL2251610
- ZINC
- ZINC000000157490
- Wikipedia
- Ethyl_salicylate
Clinical Trials
- Clinical Trials
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Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Aerosol, spray Topical Gel Topical Lotion Topical Aerosol Topical - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 3.07 mg/mL ALOGPS logP 2.76 ALOGPS logP 2.68 Chemaxon logS -1.7 ALOGPS pKa (Strongest Acidic) 9.72 Chemaxon pKa (Strongest Basic) -4.3 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 46.53 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 44.81 m3·mol-1 Chemaxon Polarizability 16.81 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 137.6243379 predictedDarkChem Lite v0.1.0 [M-H]- 137.2888379 predictedDarkChem Lite v0.1.0 [M-H]- 137.1130379 predictedDarkChem Lite v0.1.0 [M-H]- 132.70576 predictedDeepCCS 1.0 (2019) [M+H]+ 137.9322379 predictedDarkChem Lite v0.1.0 [M+H]+ 137.5225379 predictedDarkChem Lite v0.1.0 [M+H]+ 137.7632379 predictedDarkChem Lite v0.1.0 [M+H]+ 136.36584 predictedDeepCCS 1.0 (2019) [M+Na]+ 137.7332379 predictedDarkChem Lite v0.1.0 [M+Na]+ 137.2463379 predictedDarkChem Lite v0.1.0 [M+Na]+ 137.1463379 predictedDarkChem Lite v0.1.0 [M+Na]+ 145.58531 predictedDeepCCS 1.0 (2019)
Drug created at November 29, 2019 16:28 / Updated at May 14, 2021 01:07