Antimony potassium tartrate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Antimony potassium tartrate
DrugBank Accession Number
DB15587
Background

Antimony potassium tartrate is a schistosomicide possibly useful against other parasites. It has irritant emetic properties and may cause lethal cardiac toxicity among other adverse effects.

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 667.87
Monoisotopic: 665.737
Chemical Formula
C8H10K2O15Sb2
Synonyms
  • Antimony potassium tartrate
  • Potassium antimonyl D-tartrate
  • Potassium antimonyl tartrate
  • Tartar emetic
  • Tartarized antimony
  • Tartox
  • Tartrated antimony

Pharmacology

Indication

Not Available

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Associated Conditions
Indication TypeIndicationCombined Product DetailsApproval LevelAge GroupPatient CharacteristicsDose Form
Used in combination for symptomatic treatment ofCoughingCombination Product in combination with: Morphine (DB00295), Glycyrrhiza glabra (DB14312), Licorice (DB10675)••••••••••••••••••••• ••••••••••
Used in combination for symptomatic treatment ofDry throatCombination Product in combination with: Glycyrrhiza glabra (DB14312), Licorice (DB10675), Morphine (DB00295)••••••••••••••••••••• ••••••••••
Used in combination for symptomatic treatment ofPhlegmCombination Product in combination with: Glycyrrhiza glabra (DB14312), Morphine (DB00295), Licorice (DB10675)••••••••••••••••••••• ••••••••••
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as dicarboxylic acids and derivatives. These are organic compounds containing exactly two carboxylic acid groups.
Kingdom
Organic compounds
Super Class
Organic acids and derivatives
Class
Carboxylic acids and derivatives
Sub Class
Dicarboxylic acids and derivatives
Direct Parent
Dicarboxylic acids and derivatives
Alternative Parents
Monosaccharides / Fatty acids and conjugates / Organic antimony salts / Carboxylic acid salts / Carboxylic acids / Organic potassium salts / Organic oxides / Hydrocarbon derivatives / Carbonyl compounds / Alkoxides
show 1 more
Substituents
Aliphatic acyclic compound / Alkoxide / Carbonyl group / Carboxylic acid / Carboxylic acid salt / Dicarboxylic acid or derivatives / Fatty acid / Hydrocarbon derivative / Monosaccharide / Organic alkali metal salt
show 8 more
Molecular Framework
Not Available
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
DL6OZ476V3
CAS number
28300-74-5
InChI Key
WBTCZEPSIIFINA-MSFWTACDSA-J
InChI
InChI=1S/2C4H4O6.2K.3H2O.2Sb/c2*5-1(3(7)8)2(6)4(9)10;;;;;;;/h2*1-2H,(H,7,8)(H,9,10);;;3*1H2;;/q2*-2;2*+1;;;;2*+3/p-4/t2*1-,2-;;;;;;;/m11......./s1
IUPAC Name
diantimony(3+) dipotassium bis((2R,3R)-2,3-dioxidobutanedioate) trihydrate
SMILES
O.O.O.[K+].[K+].[Sb+3].[Sb+3].[O-][C@H]([C@@H]([O-])C([O-])=O)C([O-])=O.[O-][C@H]([C@@H]([O-])C([O-])=O)C([O-])=O

References

General References
Not Available
KEGG Drug
D02959
ChemSpider
32699395
RxNav
981
Wikipedia
Antimony_potassium_tartrate

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility22.4 mg/mLALOGPS
logP1.01ALOGPS
logP-1.8Chemaxon
logS-1.4ALOGPS
pKa (Strongest Acidic)2.72Chemaxon
pKa (Strongest Basic)-4.3Chemaxon
Physiological Charge-2Chemaxon
Hydrogen Acceptor Count6Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area126.38 Å2Chemaxon
Rotatable Bond Count6Chemaxon
Refractivity68.99 m3·mol-1Chemaxon
Polarizability10.22 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability1Chemaxon
Rule of FiveNoChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at December 10, 2019 19:00 / Updated at February 21, 2021 18:55