Influenza A virus A/Hong Kong/2671/2019 IVR-208 (H3N2) antigen (formaldehyde inactivated)

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Brand Names
Fluzone Quadrivalent Southern Hemisphere
Generic Name
Influenza A virus A/Hong Kong/2671/2019 IVR-208 (H3N2) antigen (formaldehyde inactivated)
DrugBank Accession Number
DB15704
Background

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen". This defence includes the production of humoral immunity through the development of antibodies (through memory B cells) and of cell-mediated immunity through the production of T-lymphocytes. Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy the virus as there are circulating antibodies that recognize that particular component of the virus that it was previously exposed to.

There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated influenza vaccine (LAIV). Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised individuals. In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques. Live vaccines maintain their replicative ability.

Type
Biotech
Groups
Approved
Biologic Classification
Vaccines
Inactivated
Synonyms
Not Available

Pharmacology

Indication

Not Available

Pharmacology
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Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

Products2
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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
FluadInfluenza A virus A/Hong Kong/2671/2019 IVR-208 (H3N2) antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza A virus A/Victoria/2454/2019 IVR-207 (H1N1) antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza B virus B/Victoria/705/2018 BVR-11 antigen (formaldehyde inactivated) (15 ug/0.5mL)Injection, suspensionIntramuscularSeqirus, Inc.2015-11-242021-07-31US flag
Fluad QuadrivalentInfluenza A virus A/Hong Kong/2671/2019 IVR-208 (H3N2) antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza A virus A/Victoria/2454/2019 IVR-207 (H1N1) antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza B virus B/Phuket/3073/2013 BVR-1B antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza B virus B/Victoria/705/2018 BVR-11 antigen (formaldehyde inactivated) (15 ug/0.5mL)Injection, suspensionIntramuscularSeqirus, Inc.2020-02-212021-07-31US flag
FLUARIX TETRAInfluenza A virus A/Hong Kong/2671/2019 IVR-208 (H3N2) antigen (formaldehyde inactivated) (15 mcg/0.5ml) + Influenza A virus A/Guangdong-Maonan/SWL1536/2019 CNIC-1909 (H1N1) antigen (formaldehyde inactivated) (15 mcg/0.5ml) + Influenza B virus B/Phuket/3073/2013 antigen (formaldehyde inactivated) (15 mcg/0.5ml) + Influenza B virus B/Washington/02/2019 antigen (formaldehyde inactivated) (15 mcg/0.5ml)Injectionบริษัท แกล็กโซสมิทไคล์น (ประเทศไทย) จำกัด2016-10-10Not applicableThailand flag
FLUZONE High-Dose Quadrivalent Northern HemisphereInfluenza A virus A/Hong Kong/2671/2019 IVR-208 (H3N2) antigen (formaldehyde inactivated) (60 ug/0.7mL) + Influenza A virus A/Guangdong-Maonan/SWL1536/2019 CNIC-1909 (H1N1) antigen (formaldehyde inactivated) (60 ug/0.7mL) + Influenza B virus B/Phuket/3073/2013 antigen (formaldehyde inactivated) (60 ug/0.7mL) + Influenza B virus B/Washington/02/2019 antigen (formaldehyde inactivated) (60 ug/0.7mL)Injection, suspensionIntramuscularSanofi Pasteur Inc.2020-07-022021-06-30US flag
Fluzone QuadrivalentInfluenza A virus A/Hong Kong/2671/2019 IVR-208 (H3N2) antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza A virus A/Guangdong-Maonan/SWL1536/2019 CNIC-1909 (H1N1) antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza B virus B/Phuket/3073/2013 antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza B virus B/Washington/02/2019 antigen (formaldehyde inactivated) (15 ug/0.5mL)Injection, suspensionIntramuscularSanofi Pasteur Inc.2020-07-022021-06-30US flag
Fluzone QuadrivalentInfluenza A virus A/Hong Kong/2671/2019 IVR-208 (H3N2) antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza A virus A/Guangdong-Maonan/SWL1536/2019 CNIC-1909 (H1N1) antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza B virus B/Phuket/3073/2013 antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza B virus B/Washington/02/2019 antigen (formaldehyde inactivated) (15 ug/0.5mL)Injection, suspensionIntramuscularSanofi Pasteur Inc.2020-07-022021-06-30US flag
Fluzone QuadrivalentInfluenza A virus A/Hong Kong/2671/2019 IVR-208 (H3N2) antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza A virus A/Guangdong-Maonan/SWL1536/2019 CNIC-1909 (H1N1) antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza B virus B/Phuket/3073/2013 antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza B virus B/Washington/02/2019 antigen (formaldehyde inactivated) (15 ug/0.5mL)Injection, suspensionIntramuscularSanofi Pasteur Inc.2020-07-022021-06-30US flag
Fluzone Quadrivalent Southern HemisphereInfluenza A virus A/Hong Kong/2671/2019 IVR-208 (H3N2) antigen (formaldehyde inactivated) (7.5 ug/0.25mL) + Influenza A virus A/Victoria/2570/2019 IVR-215 (H1N1) antigen (formaldehyde inactivated) (7.5 ug/0.25mL) + Influenza B virus B/Phuket/3073/2013 antigen (formaldehyde inactivated) (7.5 ug/0.25mL) + Influenza B virus B/Washington/02/2019 antigen (formaldehyde inactivated) (7.5 ug/0.25mL)Injection, suspensionIntramuscularSanofi Pasteur Inc.2021-02-042021-12-31US flag
Fluzone Quadrivalent Southern HemisphereInfluenza A virus A/Hong Kong/2671/2019 IVR-208 (H3N2) antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza A virus A/Victoria/2570/2019 IVR-215 (H1N1) antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza B virus B/Phuket/3073/2013 antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza B virus B/Washington/02/2019 antigen (formaldehyde inactivated) (15 ug/0.5mL)Injection, suspensionIntramuscularSanofi Pasteur Inc.2021-02-042021-12-31US flag
Fluzone Quadrivalent Southern HemisphereInfluenza A virus A/Hong Kong/2671/2019 IVR-208 (H3N2) antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza A virus A/Victoria/2570/2019 IVR-215 (H1N1) antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza B virus B/Phuket/3073/2013 antigen (formaldehyde inactivated) (15 ug/0.5mL) + Influenza B virus B/Washington/02/2019 antigen (formaldehyde inactivated) (15 ug/0.5mL)Injection, suspensionIntramuscularSanofi Pasteur Inc.2021-02-042021-12-31US flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
P8ORN3UOM6
CAS number
Not Available

References

General References
Not Available
Not Available

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4CompletedPreventionFlu caused by Influenza / Influenza, Vaccination / Vaccinations1
4CompletedPreventionInfluenza Vaccine, Influenza1
4CompletedTreatmentCerebrovascular Accident / Heart Failure / Influenza Vaccine, Influenza / Influenza, Human / Myocardial Infarction1
3RecruitingPreventionFlu caused by Influenza1
2CompletedBasic ScienceAcquired Immunodeficiency Syndrome (AIDS) Virus1
Not AvailableCompletedNot AvailableFlu caused by Influenza1
Not AvailableEnrolling by InvitationNot AvailableArsenic--Toxicology / Flu caused by Influenza / Immunologic Disorders Complicating Pregnancy / Micronutrient Deficiency / Vaccine Response Impaired1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Injection, suspensionIntramuscular; Parenteral; Subcutaneous
Injection, solutionIntramuscular
Injection, suspensionIntramuscular
Injection
SprayNasal
Injection, solutionIntramuscular; Subcutaneous
Injection, suspension
Injection, suspensionIntramuscular; Subcutaneous
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on July 29, 2020 16:52 / Updated on February 15, 2021 18:49