Lactobacillus coryniformis K8

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Lactobacillus coryniformis K8
DrugBank Accession Number
DB15733
Background

Lactobacillus is a common bacteria found in the gut with Lactobacillus coryniformis K8 being originally isolated from artisan goat cheese.

Type
Biotech
Groups
Investigational
Synonyms
  • Lc K8
External IDs
  • Lactobacillus Coryniformis K8

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action

Lactobacillus coryniformis has immunomodulatory activity. Administration of a Lc K8 probiotic prior to the influenza vaccine in adults over the age of 65 showed a higher percentage of vaccine responders and a significantly lower incidence of respiratory symptoms associated with respiratory infections.

Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
Not Available
CAS number
Not Available

References

General References
  1. Fonolla J, Gracian C, Maldonado-Lobon JA, Romero C, Bedmar A, Carrillo JC, Martin-Castro C, Cabrera AL, Garcia-Curiel JM, Rodriguez C, Sanbonmatsu S, Perez-Ruiz M, Navarro JM, Olivares M: Effects of Lactobacillus coryniformis K8 CECT5711 on the immune response to influenza vaccination and the assessment of common respiratory symptoms in elderly subjects: a randomized controlled trial. Eur J Nutr. 2019 Feb;58(1):83-90. doi: 10.1007/s00394-017-1573-1. Epub 2017 Nov 9. [Article]
Not Available

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at August 11, 2020 19:56 / Updated at February 13, 2021 10:53