This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Potassium metabisulfite
DrugBank Accession Number
DB15841
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 222.31
Monoisotopic: 221.84612843
Chemical Formula
K2O5S2
Synonyms
  • Potassium disulfite
  • Potassium metabisulfite
  • Potassium metabisulphite
  • Potassium pentaoxodisulfate
  • Potassium pyrosulfite
External IDs
  • E-224
  • INS NO.224
  • INS-224

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
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Not Available
Food Interactions
Not Available

Products

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
PROCALAMINE INJECTIONPotassium metabisulfite (<0.05 g/100 ml) + Alanine (0.21 g/100ml) + Arginine (0.29 g/100ml) + Calcium acetate (0.026 g/100ml) + Cysteine (<0.014 g/100 ml) + Glycerin (3 g/100ml) + Glycine (0.42 g/100ml) + Histidine (0.085 g/100ml) + Isoleucine (0.21 g/100ml) + Leucine (0.27 g/100ml) + Lysine acetate (0.22 g/100ml) + Magnesium acetate (0.054 g/100ml) + Methionine (0.16 g/100ml) + Phenylalanine (0.17 g/100ml) + Phosphoric acid (0.041 g/100ml) + Potassium chloride (0.15 g/100ml) + Proline (0.34 g/100ml) + Serine (0.18 g/100ml) + Sodium acetate (0.2 g/100ml) + Sodium chloride (0.12 g/100ml) + Threonine (0.12 g/100ml) + Tryptophan (0.046 g/100ml) + Valine (0.2 g/100ml)InjectionIntravenousB. BRAUN SINGAPORE PTE LTD1995-06-29Not applicable
PROCALAMINE SISE 1000 ML(SETSIZ)Potassium metabisulfite (0.05 g/100ml) + Alanine (0.21 g/100ml) + Arginine (0.29 g/100ml) + Calcium acetate monohydrate (0.026 g/100ml) + Cysteine hydrochloride (0.02 g/100ml) + Glycerin (3 g/100ml) + Glycine (0.42 g/100ml) + Histidine (0.085 g/100ml) + Isoleucine (0.21 g/100ml) + Leucine (0.27 g/100ml) + Lysine (0.22 g/100ml) + Magnesium acetate tetrahydrate (0.054 g/100ml) + Methionine (0.16 g/100ml) + Phenylalanine (0.17 g/100ml) + Phosphoric acid (0.041 g/100ml) + Potassium chloride (0.149 g/100ml) + Proline (0.34 g/100ml) + Serine (0.18 g/100ml) + Sodium acetate trihydrate (0.204 g/100ml) + Sodium chloride (0.117 g/100ml) + Threonine (0.12 g/100ml) + Tryptophan (0.046 g/100ml) + Valine (0.2 g/100ml)SolutionParenteralECZACIBAŞI-BAXTER HASTANE ÜRÜNLERİ SAN.VE TİC. A.Ş.2020-08-142017-11-02Turkey flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
PROCALAMINE SISE 1000 ML(SETLI)Potassium metabisulfite (0.05 g/100ml) + Alanine (0.21 g/100ml) + Arginine (0.29 g/100ml) + Calcium acetate monohydrate (0.026 g/100ml) + Cysteine hydrochloride (0.02 g/100ml) + Glycerin (3 g/100ml) + Glycine (0.42 g/100ml) + Histidine (0.085 g/100ml) + Isoleucine (0.21 g/100ml) + Leucine (0.27 g/100ml) + Lysine (0.22 g/100ml) + Magnesium acetate tetrahydrate (0.054 g/100ml) + Methionine (0.16 g/100ml) + Phenylalanine (0.17 g/100ml) + Phosphoric acid (0.041 g/100ml) + Potassium chloride (0.149 g/100ml) + Proline (0.34 g/100ml) + Serine (0.18 g/100ml) + Sodium acetate trihydrate (0.204 g/100ml) + Sodium chloride (0.117 g/100ml) + Threonine (0.12 g/100ml) + Tryptophan (0.046 g/100ml) + Valine (0.2 g/100ml)SolutionParenteralECZACIBAŞI-BAXTER HASTANE ÜRÜNLERİ SAN.VE TİC. A.Ş.2020-08-14Not applicableTurkey flag
PROCALAMINE SISE 500 ML(SETLI)Potassium metabisulfite (0.05 g/100ml) + Alanine (0.21 g/100ml) + Arginine (0.29 g/100ml) + Calcium acetate monohydrate (0.026 g/100ml) + Cysteine hydrochloride (0.02 g/100ml) + Glycerin (3 g/100ml) + Glycine (0.42 g/100ml) + Histidine (0.085 g/100ml) + Isoleucine (0.21 g/100ml) + Leucine (0.27 g/100ml) + Lysine (0.22 g/100ml) + Magnesium acetate tetrahydrate (0.054 g/100ml) + Methionine (0.16 g/100ml) + Phenylalanine (0.17 g/100ml) + Phosphoric acid (0.041 g/100ml) + Potassium chloride (0.149 g/100ml) + Proline (0.34 g/100ml) + Serine (0.18 g/100ml) + Sodium acetate trihydrate (0.204 g/100ml) + Sodium chloride (0.117 g/100ml) + Threonine (0.12 g/100ml) + Tryptophan (0.046 g/100ml) + Valine (0.2 g/100ml)SolutionParenteralECZACIBAŞI-BAXTER HASTANE ÜRÜNLERİ SAN.VE TİC. A.Ş.2020-08-14Not applicableTurkey flag
PROCALAMINE SISE 500 ML(SETSIZ)Potassium metabisulfite (0.05 g/100ml) + Alanine (0.21 g/100ml) + Arginine (0.29 g/100ml) + Calcium acetate monohydrate (0.026 g/100ml) + Cysteine hydrochloride (0.02 g/100ml) + Glycerin (3 g/100ml) + Glycine (0.42 g/100ml) + Histidine (0.085 g/100ml) + Isoleucine (0.21 g/100ml) + Leucine (0.27 g/100ml) + Lysine (0.22 g/100ml) + Magnesium acetate tetrahydrate (0.054 g/100ml) + Methionine (0.16 g/100ml) + Phenylalanine (0.17 g/100ml) + Phosphoric acid (0.041 g/100ml) + Potassium chloride (0.149 g/100ml) + Proline (0.34 g/100ml) + Serine (0.18 g/100ml) + Sodium acetate trihydrate (0.204 g/100ml) + Sodium chloride (0.117 g/100ml) + Threonine (0.12 g/100ml) + Tryptophan (0.046 g/100ml) + Valine (0.2 g/100ml)SolutionParenteralECZACIBAŞI-BAXTER HASTANE ÜRÜNLERİ SAN.VE TİC. A.Ş.2020-08-14Not applicableTurkey flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
65OE787Q7W
CAS number
16731-55-8
InChI Key
RWPGFSMJFRPDDP-UHFFFAOYSA-L
InChI
InChI=1S/2K.H2O5S2/c;;1-6(2)7(3,4)5/h;;(H,1,2)(H,3,4,5)/q2*+1;/p-2
IUPAC Name
dipotassium sulfinatosulfonate
SMILES
[K+].[K+].[O-]S(=O)S([O-])(=O)=O

References

General References
Not Available
ChemSpider
26061
RxNav
1362899
ChEMBL
CHEMBL2106901
Wikipedia
Potassium_metabisulfite

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
InjectionIntravenous0.21 g/100ml
SolutionParenteral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP-1.6ChemAxon
pKa (Strongest Acidic)-2.7ChemAxon
Physiological Charge-2ChemAxon
Hydrogen Acceptor Count5ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area97.33 Å2ChemAxon
Rotatable Bond Count1ChemAxon
Refractivity18.73 m3·mol-1ChemAxon
Polarizability9.14 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created at September 16, 2020 16:30 / Updated at September 16, 2020 21:10