Potassium metabisulfite
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Potassium metabisulfite
- DrugBank Accession Number
- DB15841
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 222.31
Monoisotopic: 221.84612843 - Chemical Formula
- K2O5S2
- Synonyms
- Potassium disulfite
- Potassium metabisulfite
- Potassium metabisulphite
- Potassium pentaoxodisulfate
- Potassium pyrosulfite
- External IDs
- E-224
- INS NO.224
- INS-224
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image PROCALAMINE INJECTION Potassium metabisulfite (<0.05 g/100 ml) + Alanine (0.21 g/100ml) + Arginine (0.29 g/100ml) + Calcium acetate (0.026 g/100ml) + Cysteine (<0.014 g/100 ml) + Glycerin (3 g/100ml) + Glycine (0.42 g/100ml) + Histidine (0.085 g/100ml) + Isoleucine (0.21 g/100ml) + Leucine (0.27 g/100ml) + Lysine acetate (0.22 g/100ml) + Magnesium acetate (0.054 g/100ml) + Methionine (0.16 g/100ml) + Phenylalanine (0.17 g/100ml) + Phosphoric acid (0.041 g/100ml) + Potassium chloride (0.15 g/100ml) + Proline (0.34 g/100ml) + Serine (0.18 g/100ml) + Sodium acetate (0.2 g/100ml) + Sodium chloride (0.12 g/100ml) + Threonine (0.12 g/100ml) + Tryptophan (0.046 g/100ml) + Valine (0.2 g/100ml) Injection Intravenous B. BRAUN SINGAPORE PTE LTD 1995-06-29 Not applicable Singapore PROCALAMINE SISE 1000 ML(SETSIZ) Potassium metabisulfite (0.05 g/100ml) + Alanine (0.21 g/100ml) + Arginine (0.29 g/100ml) + Calcium acetate monohydrate (0.026 g/100ml) + Cysteine hydrochloride (0.02 g/100ml) + Glycerin (3 g/100ml) + Glycine (0.42 g/100ml) + Histidine (0.085 g/100ml) + Isoleucine (0.21 g/100ml) + Leucine (0.27 g/100ml) + Lysine (0.22 g/100ml) + Magnesium acetate tetrahydrate (0.054 g/100ml) + Methionine (0.16 g/100ml) + Phenylalanine (0.17 g/100ml) + Phosphoric acid (0.041 g/100ml) + Potassium chloride (0.149 g/100ml) + Proline (0.34 g/100ml) + Serine (0.18 g/100ml) + Sodium acetate trihydrate (0.204 g/100ml) + Sodium chloride (0.117 g/100ml) + Threonine (0.12 g/100ml) + Tryptophan (0.046 g/100ml) + Valine (0.2 g/100ml) Solution Parenteral ECZACIBAŞI-BAXTER HASTANE ÜRÜNLERİ SAN.VE TİC. A.Ş. 1990-01-16 2017-11-02 Turkey - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image PROCALAMINE SISE 1000 ML(SETLI) Potassium metabisulfite (0.05 g/100ml) + Alanine (0.21 g/100ml) + Arginine (0.29 g/100ml) + Calcium acetate monohydrate (0.026 g/100ml) + Cysteine hydrochloride (0.02 g/100ml) + Glycerin (3 g/100ml) + Glycine (0.42 g/100ml) + Histidine (0.085 g/100ml) + Isoleucine (0.21 g/100ml) + Leucine (0.27 g/100ml) + Lysine (0.22 g/100ml) + Magnesium acetate tetrahydrate (0.054 g/100ml) + Methionine (0.16 g/100ml) + Phenylalanine (0.17 g/100ml) + Phosphoric acid (0.041 g/100ml) + Potassium chloride (0.149 g/100ml) + Proline (0.34 g/100ml) + Serine (0.18 g/100ml) + Sodium acetate trihydrate (0.204 g/100ml) + Sodium chloride (0.117 g/100ml) + Threonine (0.12 g/100ml) + Tryptophan (0.046 g/100ml) + Valine (0.2 g/100ml) Solution Parenteral ECZACIBAŞI-BAXTER HASTANE ÜRÜNLERİ SAN.VE TİC. A.Ş. 2013-01-29 2024-01-23 Turkey PROCALAMINE SISE 500 ML(SETLI) Potassium metabisulfite (0.05 g/100ml) + Alanine (0.21 g/100ml) + Arginine (0.29 g/100ml) + Calcium acetate monohydrate (0.026 g/100ml) + Cysteine hydrochloride (0.02 g/100ml) + Glycerin (3 g/100ml) + Glycine (0.42 g/100ml) + Histidine (0.085 g/100ml) + Isoleucine (0.21 g/100ml) + Leucine (0.27 g/100ml) + Lysine (0.22 g/100ml) + Magnesium acetate tetrahydrate (0.054 g/100ml) + Methionine (0.16 g/100ml) + Phenylalanine (0.17 g/100ml) + Phosphoric acid (0.041 g/100ml) + Potassium chloride (0.149 g/100ml) + Proline (0.34 g/100ml) + Serine (0.18 g/100ml) + Sodium acetate trihydrate (0.204 g/100ml) + Sodium chloride (0.117 g/100ml) + Threonine (0.12 g/100ml) + Tryptophan (0.046 g/100ml) + Valine (0.2 g/100ml) Solution Parenteral ECZACIBAŞI-BAXTER HASTANE ÜRÜNLERİ SAN.VE TİC. A.Ş. 2013-01-29 2024-01-23 Turkey PROCALAMINE SISE 500 ML(SETSIZ) Potassium metabisulfite (0.05 g/100ml) + Alanine (0.21 g/100ml) + Arginine (0.29 g/100ml) + Calcium acetate monohydrate (0.026 g/100ml) + Cysteine hydrochloride (0.02 g/100ml) + Glycerin (3 g/100ml) + Glycine (0.42 g/100ml) + Histidine (0.085 g/100ml) + Isoleucine (0.21 g/100ml) + Leucine (0.27 g/100ml) + Lysine (0.22 g/100ml) + Magnesium acetate tetrahydrate (0.054 g/100ml) + Methionine (0.16 g/100ml) + Phenylalanine (0.17 g/100ml) + Phosphoric acid (0.041 g/100ml) + Potassium chloride (0.149 g/100ml) + Proline (0.34 g/100ml) + Serine (0.18 g/100ml) + Sodium acetate trihydrate (0.204 g/100ml) + Sodium chloride (0.117 g/100ml) + Threonine (0.12 g/100ml) + Tryptophan (0.046 g/100ml) + Valine (0.2 g/100ml) Solution Parenteral ECZACIBAŞI-BAXTER HASTANE ÜRÜNLERİ SAN.VE TİC. A.Ş. 2013-01-29 2024-01-23 Turkey
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 65OE787Q7W
- CAS number
- 16731-55-8
- InChI Key
- RWPGFSMJFRPDDP-UHFFFAOYSA-L
- InChI
- InChI=1S/2K.H2O5S2/c;;1-6(2)7(3,4)5/h;;(H,1,2)(H,3,4,5)/q2*+1;/p-2
- IUPAC Name
- dipotassium sulfinatosulfonate
- SMILES
- [K+].[K+].[O-]S(=O)S([O-])(=O)=O
References
- General References
- Not Available
- External Links
- ChemSpider
- 26061
- 1362899
- ChEMBL
- CHEMBL2106901
- Wikipedia
- Potassium_metabisulfite
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Injection Intravenous 0.21 g/100ml Solution Parenteral - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source logP -1.6 Chemaxon pKa (Strongest Acidic) -2.7 Chemaxon Physiological Charge -2 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 97.33 Å2 Chemaxon Rotatable Bond Count 1 Chemaxon Refractivity 18.73 m3·mol-1 Chemaxon Polarizability 9.14 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 114.64542 predictedDeepCCS 1.0 (2019) [M+H]+ 116.954636 predictedDeepCCS 1.0 (2019) [M+Na]+ 123.33378 predictedDeepCCS 1.0 (2019)
Drug created at September 16, 2020 16:30 / Updated at September 16, 2020 21:10