Cetyltrimethylammonium naproxenate
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Summary
Cetyltrimethylammonium naproxenate is an anti-inflammatory and antiseptic agent indicated to treat mouth inflammation and pain , including that caused by tooth extraction.
- Generic Name
- Cetyltrimethylammonium naproxenate
- DrugBank Accession Number
- DB15877
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 513.807
Monoisotopic: 513.418194635 - Chemical Formula
- C33H55NO3
- Synonyms
- Cetyl trimethylammonium naproxenate
- Cetyltrimethylammonium naproxenate
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Symptomatic treatment of Oropharyngeal discomfort ••• ••• ••••• •••••••••• ••••• Symptomatic treatment of Oropharyngeal discomfort ••• ••• ••••• •••••••••• ••••• Symptomatic treatment of Oropharyngeal discomfort ••• ••• ••••• •••••••••• ••••• Symptomatic treatment of Oropharyngeal discomfort ••• ••• ••••• •••••••••• ••••• Symptomatic treatment of Oropharyngeal discomfort ••• ••• ••••• •••••••••• ••••• - Contraindications & Blackbox Warnings
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- International/Other Brands
- Nitens
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 5333CM4X3G
- CAS number
- 102580-74-5
- InChI Key
- RNQBLUNNAYFBIW-NPULLEENSA-M
- InChI
- InChI=1S/C19H42N.C14H14O3/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(2,3)4;1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h5-19H2,1-4H3;3-9H,1-2H3,(H,15,16)/q+1;/p-1/t;9-/m.0/s1
- IUPAC Name
- hexadecyltrimethylazanium (2S)-2-(6-methoxynaphthalen-2-yl)propanoate
- SMILES
- COC1=CC2=CC=C(C=C2C=C1)[C@H](C)C([O-])=O.CCCCCCCCCCCCCCCC[N+](C)(C)C
References
- General References
- AIFA Product Information: FLUIMUCIL GOLA (cetyltrimethylammonium naproxenate) oral [Link]
- External Links
- ChemSpider
- 52084598
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Mouthwash Oral Spray Oral - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 2.75e-06 mg/mL ALOGPS logP 6.29 ALOGPS logP 2.69 Chemaxon logS -8.3 ALOGPS Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 0 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 0 Å2 Chemaxon Rotatable Bond Count 18 Chemaxon Refractivity 104.99 m3·mol-1 Chemaxon Polarizability 41.1 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at September 23, 2020 16:30 / Updated at May 10, 2021 12:36