Carvasept
Star1
This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Summary
Carvasept is a medication used to treat hemorrhoids, anal fissures, and pruritus ani.
- Generic Name
- Carvasept
- DrugBank Accession Number
- DB15886
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 184.66
Monoisotopic: 184.0654927 - Chemical Formula
- C10H13ClO
- Synonyms
- Carvasept
- Chlorcarvacrol
- Chlorocarvacrol
- MCIT
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Used in combination to treat Anal fissures Combination Product in combination with: Levomenthol (DB00825), Ichthammol (DB11341) ••• ••• •••••••• Used in combination to treat External hemorrhoid Combination Product in combination with: Levomenthol (DB00825), Ichthammol (DB11341) ••• ••• •••••••• Used in combination to treat Hemorrhoids, internal Combination Product in combination with: Levomenthol (DB00825), Ichthammol (DB11341) ••• ••• •••••••• Used in combination to treat Pruritus ani Combination Product in combination with: Ichthammol (DB11341), Levomenthol (DB00825) ••• ••• •••••••• - Contraindications & Blackbox Warnings
- Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API
- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Delta - Hädensa - Zäpfchen Carvasept (1 mg) + Ichthammol (4 mg) + Levomenthol (50 mg) + Prednisolone (1 mg) Suppository Rectal Merz Pharma Austria Gmb H 1969-12-10 Not applicable Austria Hädensa - Salbe Carvasept (0.05 g) + Ichthammol (0.5 g) + Levomenthol (2.5 g) Ointment Topical Merz Pharma Austria Gmb H 1938-11-12 Not applicable Austria Hädensa Zäpfchen Carvasept (1 mg) + Ichthammol (4 mg) + Levomenthol (50 mg) Suppository Rectal Merz Pharma Austria Gmb H 1959-09-10 Not applicable Austria
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 5EL163606Q
- CAS number
- 5665-94-1
- InChI Key
- AFFXNOIULZQAML-UHFFFAOYSA-N
- InChI
- InChI=1S/C10H13ClO/c1-6(2)8-5-10(12)7(3)4-9(8)11/h4-6,12H,1-3H3
- IUPAC Name
- 4-chloro-2-methyl-5-(propan-2-yl)phenol
- SMILES
- CC(C)C1=C(Cl)C=C(C)C(O)=C1
References
- General References
- BASG: Hädensa (Carvasept, Ichthammol, and Levomenthol) Topical Ointment [Link]
- External Links
- ChemSpider
- 20560
- BindingDB
- 248168
- ZINC
- ZINC000000155367
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Ointment Topical Suppository Rectal - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.123 mg/mL ALOGPS logP 3.86 ALOGPS logP 4.03 Chemaxon logS -3.2 ALOGPS pKa (Strongest Acidic) 9.39 Chemaxon pKa (Strongest Basic) -6.3 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 20.23 Å2 Chemaxon Rotatable Bond Count 1 Chemaxon Refractivity 52.08 m3·mol-1 Chemaxon Polarizability 19.97 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS splash10-000i-0900000000-6cfb8bf3385662a8a822 Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS splash10-001i-9400000000-c8540608caf0a36326d3 Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS splash10-00ou-1900000000-b0bf1377c607b65988ef Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS splash10-001i-9000000000-f163696913fcf7bd37bf Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS splash10-001i-9000000000-34a3b80cb0a20fb8faf1 Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS splash10-0gz9-2900000000-540d558c5ebba9972bd8 Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at September 25, 2020 21:45 / Updated at May 07, 2021 21:08