This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Amfenac
- DrugBank Accession Number
- DB15911
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Amfenac (DB15911)
- Weight
- Average: 255.273
Monoisotopic: 255.089543283 - Chemical Formula
- C15H13NO3
- Synonyms
- (2-Amino-3-benzoylphenyl)acetic acid
- Amfenac
- Amfenaco
- Amfenacum
- External IDs
- NSC 309467
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
- Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Product Ingredients
Ingredient UNII CAS InChI Key Amfenac sodium anhydrous C20288EWAG 61941-56-8 MJAQSCHBMPGJES-UHFFFAOYSA-M
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 28O5C1J38A
- CAS number
- 51579-82-9
- InChI Key
- SOYCMDCMZDHQFP-UHFFFAOYSA-N
- InChI
- InChI=1S/C15H13NO3/c16-14-11(9-13(17)18)7-4-8-12(14)15(19)10-5-2-1-3-6-10/h1-8H,9,16H2,(H,17,18)
- IUPAC Name
- 2-(2-amino-3-benzoylphenyl)acetic acid
- SMILES
- NC1=C(CC(O)=O)C=CC=C1C(=O)C1=CC=CC=C1
References
- General References
- Not Available
- External Links
- ChemSpider
- 2051
- BindingDB
- 50225110
- ChEBI
- 75915
- ChEMBL
- CHEMBL25146
- ZINC
- ZINC000000000909
- PharmGKB
- PA166049186
- Wikipedia
- Amfenac
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Capsule 50 mg - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.0359 mg/mL ALOGPS logP 2.4 ALOGPS logP 2.89 Chemaxon logS -3.8 ALOGPS pKa (Strongest Acidic) 3.95 Chemaxon pKa (Strongest Basic) 1.77 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 80.39 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 72.64 m3·mol-1 Chemaxon Polarizability 26.13 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Drug created at November 20, 2020 19:02 / Updated at February 21, 2021 18:55