This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Summary
Thioctamide is an ingredient in nutritional products for liver health.
- Generic Name
- Thioctamide
- DrugBank Accession Number
- DB15963
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Thioctamide (DB15963)
- Weight
- Average: 205.33
Monoisotopic: 205.059506455 - Chemical Formula
- C8H15NOS2
- Synonyms
- Lipoamide
- Thioctic acid amide
- External IDs
- 213-375-2
- NSC-90787
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Contraindications & Blackbox Warnings
Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image ไลโปคอล Thioctamide (3.5 mg) + Ascorbic acid (30 mg) + Cyanocobalamin (0.001 mg) + Inositol (30 mg) + Nicotinamide (10 mg) + Orotic acid (30 mg) + Pantothenic acid (5 mg) + Pyridoxine hydrochloride (1 mg) + Racemethionine (50 mg) + Riboflavin (1 mg) + Thiamine mononitrate (2 mg) Tablet, sugar coated Oral บริษัท อินเตอร์ไทย ฟาร์มาซูติเคิ้ล แมนูแฟคเจอริ่ง จำกัด จำกัด 2005-05-13 Not applicable Thailand 
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- Q1GT04827L
- CAS number
- 940-69-2
- InChI Key
- FCCDDURTIIUXBY-UHFFFAOYSA-N
- InChI
- InChI=1S/C8H15NOS2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H2,9,10)
- IUPAC Name
- 5-(1,2-dithiolan-3-yl)pentanamide
- SMILES
- NC(=O)CCCCC1CCSS1
References
- General References
- FDA Thailand: Lipochol (Ascorbic Acid, Cyanocobalamin, Inositol, Nicotinamide, Orotic Acid, Pantothenic Acid, Pyridoxine HCl, Racemethionine, Riboflavin, Thiamine Mononitrate, Thioctamide) Oral Tablet [Link]
- External Links
- Human Metabolome Database
- HMDB0000962
- KEGG Compound
- C00248
- ChemSpider
- 840
- 1597391
- ChEBI
- 17460
- ChEMBL
- CHEMBL1403899
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Tablet, sugar coated Oral - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.101 mg/mL ALOGPS logP 2.3 ALOGPS logP 1.31 Chemaxon logS -3.3 ALOGPS pKa (Strongest Acidic) 16.45 Chemaxon pKa (Strongest Basic) -1.4 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 43.09 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 56.19 m3·mol-1 Chemaxon Polarizability 22.39 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Drug created at November 26, 2020 22:40 / Updated at May 07, 2021 21:09