Carbazochrome sulfonic acid
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Summary
Carbazochrome sulfonic acid is a hemostatic agent indicated to treat bleeding in capillary fragility.
- Generic Name
- Carbazochrome sulfonic acid
- DrugBank Accession Number
- DB15969
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 300.29
Monoisotopic: 300.052840676 - Chemical Formula
- C10H12N4O5S
- Synonyms
- Not Available
Pharmacology
- Indication
Not Available
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Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Treatment of Capillary fragility •••••••••••• ••••••• ••• ••••••••• •••••• - Contraindications & Blackbox Warnings
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Product Ingredients
Ingredient UNII CAS InChI Key Carbazochrome sodium sulfonate J0I08M946E 51460-26-5 HLFCZZKCHVSOAP-DAMYXMBDSA-M
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- BMQ12812QR
- CAS number
- 70063-04-6
- InChI Key
- OZCACMPSTYQSMM-SDQBBNPISA-N
- InChI
- InChI=1S/C10H12N4O5S/c1-14-7-4-8(15)6(12-13-10(11)16)2-5(7)3-9(14)20(17,18)19/h2,4,9H,3H2,1H3,(H3,11,13,16)(H,17,18,19)/b12-6-
- IUPAC Name
- (5Z)-5-[(carbamoylamino)imino]-1-methyl-6-oxo-2,3,5,6-tetrahydro-1H-indole-2-sulfonic acid
- SMILES
- CN1C(CC2=C\C(=N\NC(N)=O)C(=O)C=C12)S(O)(=O)=O
References
- General References
- AIFA: Adona (Carbazochrome Sulfonic Acid) Oral Tablet and Powder for Solution [Link]
- External Links
- ChemSpider
- 4864814
- ChEMBL
- CHEMBL1697827
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Injection, solution Intravenous 25 MG/5ML Powder, for solution 50 MG/100ML Tablet 25 MG Tablet 10 mg Solution Parenteral Solution Oral Injection 5 mg/mL Tablet Injection - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 2.08 mg/mL ALOGPS logP -1 ALOGPS logP -2.5 Chemaxon logS -2.2 ALOGPS pKa (Strongest Acidic) -1.3 Chemaxon pKa (Strongest Basic) 1.62 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 7 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 142.16 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 70.82 m3·mol-1 Chemaxon Polarizability 27.42 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS splash10-0udi-0069000000-a93b413109a46bacc1de Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS splash10-056r-0090000000-e66a95021af82e7057b6 Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS splash10-01ox-0971000000-556a8c5093ab4eed8bd0 Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS splash10-0a4l-5190000000-b3b257145eda5b7d94dc Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS splash10-053u-9460000000-7e2fa8da6f79c0b8c8f9 Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS splash10-0a4i-2920000000-b08ef897f9825ee57f47 Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at December 02, 2020 16:28 / Updated at May 07, 2021 21:09