Gamma-amino-beta-hydroxybutyric acid

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Gamma-amino-beta-hydroxybutyric acid is an anticonvulsant indicated to treat convulsions in children and epilepsy.

Generic Name
Gamma-amino-beta-hydroxybutyric acid
DrugBank Accession Number
DB15985
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 119.12
Monoisotopic: 119.058243154
Chemical Formula
C4H9NO3
Synonyms
  • 4-Amino-3-hydroxybutyric acid
  • Buxamine
  • Gamma-amino-beta-hydroxybutyric acid
External IDs
  • 213-106-9
  • NSC-40244

Pharmacology

Indication

Not Available

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Associated Conditions
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
1ZHM019FLD
CAS number
924-49-2
InChI Key
YQGDEPYYFWUPGO-UHFFFAOYSA-N
InChI
InChI=1S/C4H9NO3/c5-2-3(6)1-4(7)8/h3,6H,1-2,5H2,(H,7,8)
IUPAC Name
4-amino-3-hydroxybutanoic acid
SMILES
NCC(O)CC(O)=O

References

General References
  1. AIFA: Gamibetal (Gamma-amino-beta-hydroxybutyric Acid) Oral Tablet [Link]
Human Metabolome Database
HMDB0061877
KEGG Compound
C03678
ChemSpider
2064
ChEBI
16080
ChEMBL
CHEMBL93515
Wikipedia
Gamma-Amino-beta-hydroxybutyric_acid

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
TabletOral
TabletOral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility453.0 mg/mLALOGPS
logP-3.4ALOGPS
logP-3.8Chemaxon
logS0.58ALOGPS
pKa (Strongest Acidic)4.1Chemaxon
pKa (Strongest Basic)9.6Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count4Chemaxon
Hydrogen Donor Count3Chemaxon
Polar Surface Area83.55 Å2Chemaxon
Rotatable Bond Count3Chemaxon
Refractivity26.67 m3·mol-1Chemaxon
Polarizability11.35 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created at December 10, 2020 15:57 / Updated at May 07, 2021 21:09