Glycyltyrosine

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Glycyltyrosine is an ingredient in amino acid solutions for parenteral nutrition.

Generic Name
Glycyltyrosine
DrugBank Accession Number
DB15991
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 238.243
Monoisotopic: 238.095356939
Chemical Formula
C11H14N2O4
Synonyms
Not Available
External IDs
  • 211-525-1
  • NSC-83260

Pharmacology

Indication

Not Available

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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Product Ingredients
IngredientUNIICASInChI Key
Glycyltyrosine dihydrate269373P3AW39630-46-1VELZBUAWAUZDLF-WWPIYYJJSA-N
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Amino - Mel "nephro" - InfusionsflascheGlycyltyrosine (3.16 g/L) + Acetylcysteine (0.54 g/L) + Alanine (6.2 g/L) + Arginine (8.2 g/L) + Glycine (5.31 g/L) + Histidine (9.8 g/L) + Isoleucine (5.8 g/L) + Leucine (12.8 g/L) + Lysine acetate (16.93 g/L) + Methionine (2 g/L) + Phenylalanine (3.5 g/L) + Proline (3 g/L) + Serine (7.6 g/L) + Threonine (8.2 g/L) + Tryptophan (3 g/L) + Tyrosine (0.6 g/L) + Valine (8.7 g/L)SolutionIntravenousFresenius Kabi Austria Gmb H1991-03-05Not applicableAustria flag
GLAMIN SOLUTION FOR INFUSIONGlycyltyrosine (3.45 g/1000ml) + Alanine (16 g/1000ml) + Arginine (11.3 g/1000ml) + Aspartic acid (3.4 g/1000ml) + Glutamic acid (5.6 g/1000ml) + Glycylglutamine (30.27 g/1000ml) + Histidine (6.8 g/1000ml) + Isoleucine (5.6 g/1000ml) + Leucine (7.9 g/1000ml) + Lysine acetate (12.7 g/1000ml) + Methionine (5.6 g/1000ml) + Phenylalanine (5.85 g/1000ml) + Proline (6.8 g/1000ml) + Serine (4.5 g/1000ml) + Threonine (5.6 g/1000ml) + Tryptophan (1.9 g/1000ml) + Valine (7.3 g/1000ml)InjectionIntravenousFRESENIUS KABI (SINGAPORE) PTE LTD1998-07-27Not applicableSingapore flag
Glavamin InfusionslösungGlycyltyrosine (3.45 g/l) + Alanine (16 g/l) + Arginine (11.3 g/l) + Aspartic acid (3.4 g/l) + Glutamic acid (5.6 g/l) + Glycylglutamine (30.27 g/l) + Histidine (6.8 g/l) + Isoleucine (5.6 g/l) + Leucine (7.9 g/l) + Lysine acetate (12.7 g/l) + Methionine (5.6 g/l) + Phenylalanine (5.85 g/l) + Proline (6.8 g/l) + Serine (4.5 g/l) + Threonine (5.6 g/l) + Tryptophan (1.9 g/l) + Valine (7.3 g/l)SolutionParenteralFresenius Kabi Austria Gmb H1996-03-29Not applicableAustria flag
Trimix MOF Emulsion zur InfusionGlycyltyrosine dihydrate (1.725 g/1000mL) + Alanine (8 g/1000mL) + Arginine (5.65 g/1000mL) + Aspartic acid (1.7 g/1000mL) + D-glucose monohydrate (110 g/1000mL) + Fish oil (7.5 g/1000mL) + Glutamic acid (2.8 g/1000mL) + Glycylglutamine monohydrate (15.135 g/1000mL) + Histidine (3.4 g/1000mL) + Isoleucine (2.8 g/1000mL) + Leucine (3.95 g/1000mL) + Levocarnitine (1 g/1000mL) + Lysine acetate (6.35 g/1000mL) + Medium-chain triglycerides (15 g/1000mL) + Methionine (2.8 g/1000mL) + Olive oil (12.5 g/1000mL) + Phenylalanine (2.925 g/1000mL) + Proline (3.4 g/1000mL) + Serine (2.25 g/1000mL) + Soybean oil (15 g/1000mL) + Threonine (2.8 g/1000mL) + Tryptophan (0.95 g/1000mL) + Valine (3.65 g/1000mL)EmulsionParenteralFresenius Kabi Austria Gmb H2012-09-21Not applicableAustria flag
Trimix nephro Emulsion zur InfusionGlycyltyrosine (1.58 g/700mL) + Acetylcysteine (0.27 g/700mL) + Alanine (3.1 g/700mL) + Arginine (4.1 g/700mL) + Dextrose, unspecified form (60 g/700mL) + Fish oil (3 g/700mL) + Glycine (2.65 g) + Histidine (4.9 g) + Isoleucine (2.9 g/700mL) + Leucine (6.4 g/700mL) + Levocarnitine (1 g/700mL) + Lysine acetate (8.46 g/700mL) + Medium-chain triglycerides (6 g/700mL) + Methionine (1 g/700mL) + Olive oil (5 g/700mL) + Phenylalanine (1.75 g/700mL) + Proline (1.5 g/700mL) + Serine (3.8 g) + Soybean oil (6 g) + Threonine (4.1 g/700mL) + Tryptophan (1.5 g/700mL) + Tyrosine (0.3 g/700mL) + Valine (4.35 g/700mL)EmulsionParenteralFresenius Kabi Austria Gmb H2012-09-21Not applicableAustria flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
A226496H4O
CAS number
658-79-7
InChI Key
XBGGUPMXALFZOT-VIFPVBQESA-N
InChI
InChI=1S/C11H14N2O4/c12-6-10(15)13-9(11(16)17)5-7-1-3-8(14)4-2-7/h1-4,9,14H,5-6,12H2,(H,13,15)(H,16,17)/t9-/m0/s1
IUPAC Name
(2S)-2-(2-aminoacetamido)-3-(4-hydroxyphenyl)propanoic acid
SMILES
NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(O)=O

References

General References
  1. BASG: Glavamin (Amino Acids) Intravenous Solution [Link]
Human Metabolome Database
HMDB0028853
ChemSpider
83798
BindingDB
50188508
ChEBI
73517
ChEMBL
CHEMBL53400
ZINC
ZINC000001730678

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
SolutionIntravenous
InjectionIntravenous16 g/1000ml
SolutionParenteral
EmulsionParenteral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility1.84 mg/mLALOGPS
logP-2.5ALOGPS
logP-2.6Chemaxon
logS-2.1ALOGPS
pKa (Strongest Acidic)3.4Chemaxon
pKa (Strongest Basic)8.12Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count5Chemaxon
Hydrogen Donor Count4Chemaxon
Polar Surface Area112.65 Å2Chemaxon
Rotatable Bond Count5Chemaxon
Refractivity59.9 m3·mol-1Chemaxon
Polarizability23.06 Å3Chemaxon
Number of Rings1Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-001r-0910000000-488a758300ea6bc97b78
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-03gr-4910000000-e793bbe520aa4f3caf5e
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-06si-0900000000-307a8a425322f7949dd9
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-0230-6900000000-6be1169ee2af55cf82de
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-0ab9-4900000000-c8501fa42cd6cd206fbc
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-01qc-4900000000-5dbf0dfddc6df7014ad5
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-163.9423724
predicted
DarkChem Lite v0.1.0
[M-H]-151.59637
predicted
DeepCCS 1.0 (2019)
[M+H]+164.7623724
predicted
DarkChem Lite v0.1.0
[M+H]+153.95439
predicted
DeepCCS 1.0 (2019)
[M+Na]+164.7163724
predicted
DarkChem Lite v0.1.0
[M+Na]+160.04759
predicted
DeepCCS 1.0 (2019)

Drug created at December 10, 2020 17:10 / Updated at May 05, 2021 20:32