Methane

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Methane is a gas indicated in combination with others to determine lung volume and pulmonary blood flow.

Generic Name
Methane
DrugBank Accession Number
DB15994
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Thumb
Weight
Average: 16.0425
Monoisotopic: 16.031300128
Chemical Formula
CH4
Synonyms
Not Available
External IDs
  • 200-812-7

Pharmacology

Indication

Not Available

Pharmacology
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Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Medicalerrors
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Categories

Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as alkanes. These are acyclic branched or unbranched hydrocarbons having the general formula CnH2n+2 , and therefore consisting entirely of hydrogen atoms and saturated carbon atoms.
Kingdom
Organic compounds
Super Class
Hydrocarbons
Class
Saturated hydrocarbons
Sub Class
Alkanes
Direct Parent
Alkanes
Alternative Parents
Not Available
Substituents
Acyclic alkane / Aliphatic acyclic compound / Alkane
Molecular Framework
Aliphatic acyclic compounds
External Descriptors
one-carbon compound, mononuclear parent hydride, alkane (CHEBI:16183) / a simple group (METHYL-GROUP)
Affected organisms
Not Available

Chemical Identifiers

UNII
OP0UW79H66
CAS number
74-82-8
InChI Key
VNWKTOKETHGBQD-UHFFFAOYSA-N
InChI
InChI=1S/CH4/h1H4
IUPAC Name
methane
SMILES
C

References

General References
  1. BASG: iCOmas (Acetylene, Carbon Monoxide, Methane) Inhalation Gas [Link]
Human Metabolome Database
HMDB0002714
KEGG Compound
C01438
ChemSpider
291
ChEBI
16183
ChEMBL
CHEMBL17564
PDBe Ligand
74C
Wikipedia
Methane
PDB Entries
5ls7

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
3RecruitingTreatmentMetastatic Melanoma / Recurrent Melanoma / Stage III Cutaneous Melanoma AJCC v7 / Stage IIIA Cutaneous Melanoma AJCC v7 / Stage IIIB Cutaneous Melanoma AJCC v7 / Stage IIIC Cutaneous Melanoma AJCC v7 / Stage IV Cutaneous Melanoma AJCC v6 and v7 / Unresectable Cutaneous Melanoma1
2Active Not RecruitingTreatmentAdvanced Lymphomas / Advanced Malignant Solid Neoplasm / Hematopoietic and Lymphoid Cell Neoplasm / Refractory Lymphomas / Refractory Malignant Solid Neoplasm / Refractory Plasma Cell Myeloma1
2Active Not RecruitingTreatmentClinical Stage IV Cutaneous Melanoma AJCC v8 / Locally Advanced Melanoma / Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 / Pathologic Stage IV Cutaneous Melanoma AJCC v8 / Unresectable Melanoma1
2Active Not RecruitingTreatmentStage III Cutaneous Melanoma AJCC v7 / Stage IIIA Cutaneous Melanoma AJCC v7 / Stage IIIB Cutaneous Melanoma AJCC v7 / Stage IIIC Cutaneous Melanoma AJCC v7 / Stage IV Cutaneous Melanoma AJCC v6 and v7 / Unresectable Melanoma1
2CompletedTreatmentAdenocarcinomas / Neoplasms, Pancreatic1
2RecruitingTreatmentAdvanced Malignant Solid Neoplasm / Bladder Carcinoma / Carcinoma, Breast / Carcinoma, Colorectal / Carcinoma, Pancreatic / Cervical Carcinoma / Colon Carcinoma / Endometrial Carcinoma / Esophageal Carcinoma / Gastric Carcinoma / Gliomas / Head and Neck Carcinoma / Liver and Intrahepatic Bile Duct Carcinoma / Lung, Carcinoma / Malignant Lymphomas / Malignant Uterine Neoplasm / Melanomas / Ovarian Carcinoma / Plasma Cell Myeloma / Prostate Cancer / Rectal Carcinoma / Recurrent Bladder Carcinoma / Recurrent Breast Carcinoma / Recurrent Cervical Carcinoma / Recurrent Colon Carcinoma / Recurrent Colorectal Carcinoma / Recurrent Esophageal Carcinoma / Recurrent Gastric Carcinoma / Recurrent Gliomas / Recurrent Head and Neck Carcinoma / Recurrent Liver Carcinoma / Recurrent Lung Carcinoma / Recurrent Lymphoma / Recurrent Malignant Solid Neoplasm / Recurrent Melanoma / Recurrent Ovarian Carcinoma / Recurrent Pancreatic Carcinoma / Recurrent Plasma Cell Myeloma / Recurrent Prostate Carcinoma / Recurrent Rectal Carcinoma / Recurrent Skin Carcinoma / Recurrent Thyroid Gland Carcinoma / Recurrent Uterine Corpus Cancer / Refractory Lymphomas / Refractory Malignant Solid Neoplasm / Refractory Plasma Cell Myeloma / Renal Carcinoma / Skin Carcinoma / Thyroid Gland Carcinoma / Uterine Corpus Cancer1
2RecruitingTreatmentAnaplastic Astrocytoma (AA) / Anaplastic Ganglioglioma / Glioblastomas / Gliomas, Malignant / Pleomorphic Xanthoastrocytoma, Anaplastic / WHO Grade III Glioma1
2WithdrawnTreatmentErdheim-Chester Disease (ECD)1
1Active Not RecruitingTreatmentMetastatic Thyroid Gland Carcinoma / Unresectable Thyroid Gland Carcinoma1
1, 2Active Not RecruitingTreatmentHematopoietic and Lymphoid Cell Neoplasm / Locally Advanced Malignant Solid Neoplasm / Locally Advanced Melanoma / Metastatic Malignant Solid Neoplasm / Metastatic Melanoma / Stage IIIC Cutaneous Melanoma AJCC v7 / Stage IV Cutaneous Melanoma AJCC v6 and v7 / Unresectable Malignant Solid Neoplasm / Unresectable Melanoma1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
GasRespiratory (inhalation)
Prices
Not Available
Patents
Not Available

Properties

State
Gas
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.0 mg/mLALOGPS
logP-1.3ALOGPS
logP1.08ChemAxon
logS1.08ALOGPS
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity6.35 m3·mol-1ChemAxon
Polarizability2.59 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSNot Available
GC-MS Spectrum - EI-BGC-MSsplash10-014i-9000000000-42e2bf163f3e1178d2b7
Mass Spectrum (Electron Ionization)MSsplash10-014i-9000000000-349ab823203cc040e2ee
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-014i-9000000000-9d8342b86bcfe423c16e
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-014i-9000000000-9d8342b86bcfe423c16e
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-014i-9000000000-9d8342b86bcfe423c16e
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-014i-9000000000-c888af3d1348fef91ee6
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-014i-9000000000-c888af3d1348fef91ee6
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-014i-9000000000-c888af3d1348fef91ee6
1H NMR Spectrum1D NMRNot Applicable

Drug created on December 10, 2020 19:31 / Updated on May 05, 2021 20:32