Potassium hydrogen DL-aspartate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Potassium hydrogen DL-aspartate is a medication indicated to treat combined potassium-magnesium deficiency with subsequent arrhythmia.

Generic Name
Potassium hydrogen DL-aspartate
DrugBank Accession Number
DB15998
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 171.193
Monoisotopic: 170.99338917
Chemical Formula
C4H6KNO4
Synonyms
Not Available

Pharmacology

Indication

Not Available

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Associated Conditions
Indication TypeIndicationCombined Product DetailsApproval LevelAge GroupPatient CharacteristicsDose Form
Used in combination to treatArrhythmia caused by combined magnesium and potassium deficiencyCombination Product in combination with: Magnesium aspartate (DB13359)•••••••••••••••••••••• ••••••
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Trommcardin - FilmtablettenPotassium hydrogen DL-aspartate (360 mg) + Magnesium aspartate (360 mg)Tablet, film coatedOralJacoby Gm Pharma Gmb H1972-04-11Not applicableAustria flag
Trommcardin K 120 - InfusionsflaschePotassium hydrogen DL-aspartate (30 mmol) + Magnesium aspartate (7.5 mmol)Injection, solutionIntravenousJacoby Gm Pharma Gmb H1978-01-16Not applicableAustria flag

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
5UW00M8KR0
CAS number
923-09-1
InChI Key
TXXVQZSTAVIHFD-UHFFFAOYSA-M
InChI
InChI=1S/C4H7NO4.K/c5-2(4(8)9)1-3(6)7;/h2H,1,5H2,(H,6,7)(H,8,9);/q;+1/p-1
IUPAC Name
potassium 3-amino-3-carboxypropanoate
SMILES
[K+].NC(CC([O-])=O)C(O)=O

References

General References
  1. BASG: Trommcardin (Magnesium Aspartate, Potassium Hydrogen DL-Aspartate) Oral Tablet [Link]
  2. BASG: Trommcardin (Magnesium Aspartate, Potassium Hydrogen DL-Aspartate) Intravenous Injection [Link]
ChemSpider
19957263

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Tablet, film coatedOral
Injection, solutionIntravenous
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility515.0 mg/mLALOGPS
logP-2.8ALOGPS
logP-3.5Chemaxon
logS0.48ALOGPS
pKa (Strongest Acidic)1.7Chemaxon
pKa (Strongest Basic)9.61Chemaxon
Physiological Charge-1Chemaxon
Hydrogen Acceptor Count5Chemaxon
Hydrogen Donor Count2Chemaxon
Polar Surface Area103.45 Å2Chemaxon
Rotatable Bond Count3Chemaxon
Refractivity37.37 m3·mol-1Chemaxon
Polarizability10.99 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at December 10, 2020 20:26 / Updated at May 05, 2021 20:32