NAV

Testosterone decanoate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Testosterone decanoate is a steroid indicated for testosterone replacement therapy in sterilization, missing testicle, hypopituitarism, and osteoporosis.

Generic Name
Testosterone decanoate
DrugBank Accession Number
DB16001
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
3D
Similar Structures
Weight
Average: 442.684
Monoisotopic: 442.344695341
Chemical Formula
C29H46O3
Synonyms
Not Available
External IDs
  • 227-226-4
  • NSC-26642
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Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
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interactions in your software
Beclomethasone dipropionateThe risk or severity of edema formation can be increased when Testosterone decanoate is combined with Beclomethasone dipropionate.
BetamethasoneThe risk or severity of edema formation can be increased when Testosterone decanoate is combined with Betamethasone.
Betamethasone phosphateThe risk or severity of edema formation can be increased when Testosterone decanoate is combined with Betamethasone phosphate.
BudesonideThe risk or severity of edema formation can be increased when Testosterone decanoate is combined with Budesonide.
CiclesonideThe risk or severity of edema formation can be increased when Testosterone decanoate is combined with Ciclesonide.
Food Interactions
Not Available

Products

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
SUSTANON 250 INJECTIONTestosterone decanoate (100 mg/ml) + Testosterone isocaproate (60 mg/ml) + Testosterone phenylpropionate (60 mg/ml) + Testosterone propionate (30 mg/ml)InjectionIntramuscularDCH AURIGA SINGAPORE1990-05-31Not applicableSingapore flag
TEST - COMP 250Testosterone decanoate (100 mg/mL) + Testosterone isocaproate (60 mg/mL) + Testosterone phenylpropionate (60 mg/mL) + Testosterone propionate (30 mg/mL)Injection, solutionบริษัท กรุงเทพ ฟาร์มา ดิสทริบิวชั่น จำกัด2018-06-06Not applicableThailand flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
IJW60LAO6S
CAS number
5721-91-5
InChI Key
LBERVHLCXUMDOT-MPZZESAYSA-N
InChI
InChI=1S/C29H46O3/c1-4-5-6-7-8-9-10-11-27(31)32-26-15-14-24-23-13-12-21-20-22(30)16-18-28(21,2)25(23)17-19-29(24,26)3/h20,23-26H,4-19H2,1-3H3/t23-,24-,25-,26-,28-,29-/m0/s1
IUPAC Name
(1S,3aS,3bR,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl decanoate
SMILES
[H][C@@]12CC[C@H](OC(=O)CCCCCCCCC)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C

References

General References
  1. FDA Thailand: Test - Comp 250 (Testosterone Decanoate, Testosterone Isocaproate, Testosterone Phenylpropionate, Testosterone Propionate) Injection [Link]
KEGG Compound
C14607
ChemSpider
136680
RxNav
37858
ChEBI
35000
ChEMBL
CHEMBL1473654
ZINC
ZINC000019685816
Wikipedia
Testosterone_decanoate

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
InjectionIntramuscular100 mg/ml
Injection, solution
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.000114 mg/mLALOGPS
logP6.3ALOGPS
logP7.62Chemaxon
logS-6.6ALOGPS
pKa (Strongest Acidic)18.52Chemaxon
pKa (Strongest Basic)-4.8Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area43.37 Å2Chemaxon
Rotatable Bond Count10Chemaxon
Refractivity130.42 m3·mol-1Chemaxon
Polarizability54.86 Å3Chemaxon
Number of Rings4Chemaxon
Bioavailability1Chemaxon
Rule of FiveNoChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleYesChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-0006-2231900000-5da9e49c6dd6724d1947
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-0006-0000900000-31a5a89fba6752954a48
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-0006-0220900000-6e81fcafe27fc673ca62
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-05i3-9654500000-7907180f1ba2526ce756
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-0bvm-9811500000-49f6486ee81aa28bc107
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-0ac3-8922100000-42095a2b488669deeb32
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-232.7446331
predicted
DarkChem Lite v0.1.0
[M-H]-216.40869
predicted
DeepCCS 1.0 (2019)
[M+H]+232.8541331
predicted
DarkChem Lite v0.1.0
[M+H]+218.3041
predicted
DeepCCS 1.0 (2019)
[M+Na]+233.1031331
predicted
DarkChem Lite v0.1.0
[M+Na]+224.04639
predicted
DeepCCS 1.0 (2019)

Drug created at December 10, 2020 20:58 / Updated at May 05, 2021 20:32