Luvadaxistat

DB16067InvestigationalSmall molecule

Luvadaxistat is under investigation in clinical trial NCT03214588 (Efficacy, Tolerability, and Pharmacokinetics of Multiple Doses of Oral TAK-831 in Adults With Friedreich Ataxia).

Chemical structure of Luvadaxistat
Formula / weight
C13H11F3N2O2 · 284.238 g/mol (avg)
Also known as
3(2H)-PYRIDAZINONE, 4-HYDROXY-6-(2-(4-(TRIFLUOROMETHYL)PHENYL)ETHYL)- · 4-HYDROXY-6-(2-(4-(TRIFLUOROMETHYL)PHENYL)ETHYL)-2,3-DIHYDROPYRIDAZIN-3-ONE
Code names
TAK-831

Resolves to

Compound
UNII76IC00YRVRCAS1425511-32-5ChEMBLCHEMBL2338801
Structure
InChIKeyQBQMUMMSYHUDFM-UHFFFAOYSA-NSMILESOC1=CC(CCC2=CC=C(C=C2)C(F)(F)F)=NNC1=O
Targets
P14920DAO

What you can answer from here — as of April 23, 2025

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
8Clinical trialsPhase, status and sponsor resolved per trial
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1+ReferenceStructured and connected to the statements they support
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Which drugs share a target with Luvadaxistat, and which of those have an active Phase 3 trial?

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