Dynorphin

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DB16146InvestigationalSmall molecule

Dynorphin is under investigation in clinical trial NCT00000244 (Effects of Dynorphin 1-13 on Heroin Addiction - 1).

Formula / weight: C₉₉H₁₅₅N₃₁O₂₃ · 2147.523 g/mol (avg)
Also known as: Dynorphin a · Dynorphin a (1-17) · Dynorphin a (bos taurus) · Dynorphin a (human) · Dynorphin a (pig)
Code names: DYN-A17

Resolves to

Compound

UNII9M18T0TD14CAS80448-90-4ChEMBLCHEMBL411557

Structure

InChIKeyJMNJYGMAUMANNW-FIXZTSJVSA-NSMILES

[H][C@](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)CC1=CC=C(O)C=C1)([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(O)=O

Targets

P41145OPRK1P41143OPRD1P35372OPRM1

What you can answer from here — as of April 23, 2025

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

1Clinical trialPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Dynorphin, and which of those have an active Phase 3 trial?

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