This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Efavaleukin alfa
DrugBank Accession Number
DB16149
Background

Efavaleukin alfa is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With Steroid Refractory Chronic Graft Versus Host Disease).

Type
Biotech
Groups
Investigational
Synonyms
  • Efavaleukin alfa
  • Fc il-2 mutein fusion protein (amg-592)
  • Immunoglobulin g1 (fc domain-containing fragment) fusion protein with peptide (synthetic linker) fusion protein with interleukin 2 (synthetic human mutein), dimer
External IDs
  • AMG 592
  • AMG-592

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
YNH9K62UXU
CAS number
2049067-94-7

References

General References
Not Available
Not Available

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2RecruitingTreatmentActive Systemic Lupus Erythematosus1
2RecruitingTreatmentUlcerative Colitis1
1CompletedBasic ScienceSystemic Lupus Erythematosus (SLE)1
1CompletedTreatmentInflammatory Diseases1
1, 2CompletedTreatmentChronic Graft Versus Host Disease cGVHD1
1, 2TerminatedTreatmentRheumatoid Arthritis1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at December 15, 2020 18:13 / Updated at February 21, 2021 18:55