Imaradenant

DB16192InvestigationalSmall molecule

Imaradenant is under investigation in clinical trial NCT03381274 (Oleclumab (MEDI9447) Egfrm NSCLC Novel Combination Study).

Chemical structure of Imaradenant
Mechanism
Curator reviewed
Formula / weight
C15H11ClFN5 · 315.74 g/mol (avg)
Code names
AZD-4635 · HTL-1071

Resolves to

Compound
UNII770140J08ACAS1321514-06-0
Structure
InChIKeyNCWQLHHDGDXIJN-UHFFFAOYSA-NSMILESCC1=NC(Cl)=CC(=C1)C1=NN=C(N)N=C1C1=CC=C(F)C=C1
Targets
P29274ADORA2A

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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6Clinical trialsPhase, status and sponsor resolved per trial
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6+ReferencesStructured and connected to the statements they support
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