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DB16219InvestigationalSmall molecule
Levonadifloxacin is under investigation in clinical trial NCT03405064 (Comparative Study of Levonadifloxacin (IV and Oral) With Linezolid (IV and Oral) in Acute Bacterial Skin and Skin Structure Infections (ABSSSI)).
- Mechanism
- Curator reviewed
Pharmacologically active on DNA gyrase subunit B, DNA topoisomerase 4 subunit A, and DNA gyrase subunit A
- Formula / weight
- C19H21FN2O4 · 360.385 g/mol (avg)
- Also known as
- (s)-(-)-nadifloxacin · Nadifloxacin, (s)- · Wck 771 free base · Wck-771 free base · Wck771 free base
Resolves to
Clinical / RWD
Structure
InChIKey
JYJTVFIEFKZWCJ-JTQLQIEISA-NSMILESC[C@H]1CCC2=C(N3CCC(O)CC3)C(F)=CC3=C2N1C=C(C(O)=O)C3=OWhat you can answer from here — as of July 08, 2026
3Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
Which drugs share a target with Levonadifloxacin, and which of those have an active Phase 3 trial?