TAK-653

DB16304InvestigationalSmall molecule

TAK-653 is under investigation in clinical trial NCT03312894 (Efficacy and Safety of TAK-653 in Treatment-resistant Depression).

Chemical structure of TAK-653
Mechanism
Curator reviewed
Formula / weight
C19H23N3O3S · 373.47 g/mol (avg)
Code names
TAK-653

Resolves to

Compound
UNII9E3TOE5RIZCAS1358751-06-0
Structure
InChIKeyPXJBHEHFVQVDDS-UHFFFAOYSA-NSMILESCC1=CN2CCS(=O)(=O)N=C2C(=N1)C1=CC=C(OC2CCCCC2)C=C1
Targets
P42261GRIA1

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
5Clinical trialsPhase, status and sponsor resolved per trial
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1+ReferenceStructured and connected to the statements they support
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