Matrix-M
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Matrix-M
- DrugBank Accession Number
- DB16369
- Background
Matrix-M is a saponin-based adjuvant made of nanometer particles, cholesterol, and phospholipid that is developed by Novavax.1 This compound is administered alongside vaccines to enhance biological functions: creating robust and long-lasting immune responses that may allow for dose-sparing of vaccines.
- Type
- Biotech
- Groups
- Investigational
- Synonyms
- Matrix-M1
- Matrix-M1 Adjuvant
- External IDs
- Matrix-M
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
Matrix-M can enhance activated T-cell, B-cell, and antigen-presenting cell populations by inducing the influx of antigen-presenting cells.1 It can also enhance both B-cell immunity and T-cell immunity.
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- YZ7P8Y8ECX
- CAS number
- Not Available
References
- General References
- Novavax: Novavax addresses urgent global public health needs with innovative technology [Link]
- External Links
- Not Available
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 4 Not Yet Recruiting Prevention Plasmodium Falciparum, Malaria 1 3 Active Not Recruiting Prevention Coronavirus Disease 2019 (COVID‑19) 2 3 Active Not Recruiting Prevention Malaria 1 3 Completed Prevention Coronavirus Disease 2019 (COVID‑19) 2 3 Completed Prevention Coronavirus Disease 2019 (COVID‑19) / Seasonal Allergic Rhinitis 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
Drug created at December 20, 2020 03:30 / Updated at December 20, 2020 03:42