Sibofimloc

DB16400InvestigationalSmall molecule

Sibofimloc is under investigation in clinical trial NCT03943446 (TAK-018 for Prevention of the Recurrence of Postoperative Crohn's Disease (CD)).

Chemical structure of Sibofimloc
Formula / weight
C35H39NO11 · 649.693 g/mol (avg)
Code names
EB-8018 · VRT-1353385 · WHO 10950

Resolves to

Compound
UNII00OF00QZC4CAS1616113-45-1
Structure
InChIKeySFHMWDMKUYVSQJ-VECBPBMLSA-NSMILES[H][C@@]1(O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O)C#CC1=CC=C2C3=CC=C(C=C3C3(CCN(CC3)C(C)=O)C2=C1)C#C[C@@]1([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O

What you can answer from here — as of April 23, 2025

3Clinical trialsPhase, status and sponsor resolved per trial
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Which companies are running trials of Sibofimloc, in which indications and phases, and which of those programs are still active?

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