Tin protoporphyrin IX

DB16449InvestigationalSmall molecule

Tin protoporphyrin IX: Overview.

Mechanism: SnPP is a competitive inhibitor of heme oxygenase, an enzyme which degrades heme to bilirubin, prevents the development of hyperbilirubinemia, and reduces bilirubin levels in plasma. This compound is also found to directly inactivate DENV and YFV infectious particles and has the potential to have antiviral activity against numerous organisms.
Curator reviewed
Formula / weight: C₃₄H₃₂Cl₃N₄O₄Sn · 785.71 g/mol (avg)
Also known as: Dihydrogen (OC-6-13)-dichloro[7,12-diethenyl-3,8,13,17-tetramethylporphyrin-2,18-dipropionato(4-)-N21,N22,N23,N24]stannate(2-)- · Sn Protoporphyrin · Sn-heme · SnPP · SnPP Protoporphyrin
Code names: GTPL5279 · Q27088994

Resolves to

Compound

Structure

[Cl-].[Cl-].[Sn+4].CC1=C(CCC([O-])=O)/C2=C/C3=N/C(=C\C4=C(C)C(C=C)=C(N4)/C=C4\N=C(\C=C\1/N\2)C(C=C)=C4C)/C(C)=C3CCC([O-])=O

Targets

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

13+ReferencesStructured and connected to the statements they support

Which drugs share a target with Tin protoporphyrin IX, and which of those have an active Phase 3 trial?

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