DB16467InvestigationalNucleic Acid Based Therapies
Polyinosinic-polycytidylic acid: Overview.
- Mechanism
- Curator reviewed
Polyinosinic:polycytidylic acid is an analog of double-stranded RNA with potential to act as a vaccine adjuvant to enhance innate and adapative immune responses. It activates toll-like receptor 3 (TLR3) and retinoic acid inducible gene 1 (RIG-I)-like receptors, which has been shown to trigger apoptosis in cancer cells.
- Also known as
- Poly I-C · Poly I:C · Poly(I:C) · Poly(I+C)
- Code names
- BO-112
Resolves to
Compound
Clinical / RWD
Targets
What you can answer from here — as of September 12, 2026
1Protein targetEach mapped to UniProt, with action and pharmacological actionListed above
Which drugs share a target with Polyinosinic-polycytidylic acid, and which of those have an active Phase 3 trial?
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