AT-301

Identification

Generic Name
AT-301
DrugBank Accession Number
DB16507
Background

AT-301 was under investigation in clinical trial NCT01675284 to evaluate the safety, reactogenicity, and humoral immune responses to an inactivated H5N1 influenza vaccine

Type
Biotech
Groups
Investigational
Biologic Classification
Vaccines
Inactivated
Synonyms
Not Available
External IDs
  • AT-301

Pharmacology

Indication

Not Available

Reduce drug development failure rates
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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action

AT-301 is a proprietary nasal formula developed by Atossa intended for administration in patients diagnosed with COVID-19 who do not have symptoms severe enough for hospitalization. This formulation aims to prevent infection by potentially interfering with spike protein activation through host proteases, by masking receptor binding domains, and by providing a generalized mucoadhesive epithelial barrier to block the entry of the SARS-CoV-2 viral gene proteins in the nasal epithelial cells. AT-301 is currently being investigated against COVID-19.

Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
Not Available
CAS number
Not Available

References

General References
  1. External Link [Link]
  2. External Link [Link]
Not Available

Clinical Trials

Clinical Trials
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PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns
1CompletedPreventionInfluenza A(H5N1) / Influenza, Avian1somestatusstop reasonjust information to hide

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at January 21, 2021 02:02 / Updated at July 13, 2024 15:36